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Showing 1 to 9 of 9 for “"anthrax toxin"”.

  1. Anthrax toxin effects on B lymphocyte function

    Bryan Thomas GnadeThe University of Texas Medical Branch2010

    … cutaneous, gastrointestinal and inhalational anthrax. It has a number of virulence factors of which, the two toxins are of great importance. Lethal toxin is a zinc metaloprotease that cleaves the N terminus of the mitogen-activated protein kinase (MAPK) kinase family 1-7, with the exception of …

    utmb Repository record

  2. 19F-NMR studies on anthrax toxin protective antigen

    Chadegani, Fatemeh2014

    wichita-thes

  3. Delivery of biomolecules into mammalian cells using anthrax toxin

    Rabideau, Amy EllenMassachusetts Institute of Technology2015

    … a non-toxic delivery platform derived from anthrax lethal toxin has been developed to overcome this challenge for the delivery of biomolecules into the cytosol of mammalian cells. The PA/LFN delivery platform has been used to deliver over 30 known biomolecules of diverse sequences, …

    mit Repository record

  4. Structural and stability studies on domain IV of anthrax toxin protective antigen (PA); its role in anthrax pathogenesis

    Mamillapalli, Sireesha2018

    wichita-thes

  5. Control of The Master Virulence Regulatory Gene Atxa In Bacillus Anthracis

    Dale, Jennifer L2012

    … anthracis</em> structural genes for the anthrax toxin proteins and biosynthetic operon for capsule are positively regulated by AtxA, a transcription regulator with unique properties. Consistent with the role of <em>atxA</em> in virulence factor expression, a <em>B. anthracis</em> …

    uthsc Repository record

  6. The Immune Inhibitor A1 Protease of <em>Bacillus Anthracis</em>

    Pflughoeft, Kathryn2011

    … in the soil and the causative agent of anthrax, utilizes multiple mechanisms to regulate secreted factors; one example is the activity of secreted proteases. One of the most abundant proteins in the culture supernates of <em>B. anthracis</em> is the Immune Inhibitor A1 (InhA1) protease. …

    uthsc Repository record

  7. Biochemical characterisation of the translocation of material through the protective antigen (PA) Pore

    Shorter, Susan AmandaUniversity of Greenwich2017

    … a tripartite protein complex, forming the toxin known as anthrax toxin. It is composed of the catalytically active proteins, lethal factor (LF) and oedema factor (EF), and protective antigen of 83 kDa (PA83). This toxin complex mediates cytosolic entry through the formation of an oligomeric …

    greenwich Repository record

  8. Functional Characterization of Atxa, The Bacillus Anthracis Virulence Regulator

    Hammerstrom, Troy G.2012

    … from studies of AtxA-induced synthesis of the anthrax toxin proteins and the poly-D-glutamic acid capsule, two factors with important roles in <em>B. anthracis</em> pathogenesis. The amino-terminal region of the AtxA protein contains winged-helix (WH) and helix-turn-helix (HTH) motifs, …

    uthsc Repository record

  9. Roles of Small Rnas and Paralogous Proteins In Bacillus Anthracis Virulence Gene Regulation

    Corsi, Ileana, <p>http://www.orcid.org/0000-0002-5422-9105</p>2023

    … anthracis</em>, the causative agent of anthrax. The sRNAs, named “XrrA and XrrB” (for p­XO1-encoded regulatory RNA) are abundant and highly stable primary transcripts, whose expression is dependent upon AtxA, the master virulence regulator of <em>B. anthracis</em>. sRNA levels are …

    uthsc Repository record