Global ETD Search
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Showing 1 to 2 of 2 for “"ankyrin-B"”.
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Defining Ankyrin-b Syndrome: Characterization of Ankyrin-b Variants in Mice and Men and the Discovery of a Role for Ankyrin-b in Parasympathetic Control of Insulin Release
<p>Studies in the ankyrin-B+/- mouse reveal that ankyrin-B deficiency is associated with both the benefits of enhanced cardiac contractility and the costs of arrhythmia, early senescence, reduced lifespan, and impaired glucose tolerance. This constellation of traits is known as ankyrin-B syndrome, …
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Ankyrin-B and Mtor Complex 1 In The Regulation of Electrical Activities In The Heart
… in the brain and heart is the adaptor protein ankyrin. In the heart, ankyrin-B targets and maintains the membrane expression of ion channels and transporters that are critical for maintaining calcium ion homeostasis, which underlies normal excitation-contraction coupling. Sustained mTORC1 …