Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 14 of 14 for “"angiotensin-converting-enzyme inhibitor"”.
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Combination Treatment of Angiotensin-II Receptor Blocker and Angiotensin-Converting-Enzyme Inhibitor in Non-Diabetic Renal Disease on Effect of Reducing Proteinuria
BACKGROUND: The fact that angiotensin-converting enzyme inhibitors(ACEI) and angiotensin receptor blockers(ARB) antagonize the renin-angiotensin system at different levels suggests that these agents, already confirmed by clinical benefit in retarding the progression of chronic renal disease, may …
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Evaluating adherence to recommended clinical guidelines for the prevention of cardiovascular disease in patients with Type 2 diabetes mellitus at primary care level
… managed with first-line- medication - an Angiotensin Converting Enzyme Inhibitor (ACEI). There was appropriate supporting documentation for only 39% not on first line therapy. A fifth (22%) with drug intolerance received the recommended alternative. Most were appropriately prescribed a …
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Impact Of Time-Varying And Time-Invariant Measures Of Adherence To Secondary Prevention Therapies Post-Acute Myocardial Infarction: An Application Of Marginal Structural Models (MSMS)
… and cohorts B (β-blocker therapy) and C (angiotensin converting enzyme inhibitor (ACEI)/angiotensin receptor blocker (ARB) therapy) included 1,021 and 1,025 patients, respectively. When accounting only for baseline covariates in a discrete-event time model the hazard for a recurrent AMI …
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The effects of right ventricular pacing in the heart failure population
… data-linkage study demonstrated that <br/>angiotensin receptor blocker or angiotensin converting enzyme inhibitor use <br/>was associated with improved mortality and less hospitalisation for heart <br/>failure in patients paced for complete heart block, who were likely to be <br/>exposed to …
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Establishing models of and characterising the genomic context of neutrophil hypersegmentation
… via an investigation of the impact of the angiotensin converting enzyme inhibitor (ACEi) captopril, glucose concentration, and hypoxia. Furthermore, the current work outlines the optimisation of a laser capture microdissection (LCM) technique for the isolation of neutrophils, based on their …
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Apoptosis in the equine small intestine following experimental ischemia-reperfusion injury
… injury and determining if use of an angiotensin converting enzyme inhibitor (enalaprilat) would ameliorate the apoptotic response. It was designed to determine if mucosal epithelial cells undergo apoptosis during the ischemia phase and also examined if apoptosis is significantly …
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Dapagliflozin Regresses Left Ventricular Hypertrophy in People with Type 2 Diabetes
… mortality. Sodium–glucose cotransporter 2 inhibitors (SGLT2i) have been shown to reduce cardiovascular events, particularly heart failure, in cardiovascular outcome trials. One potential mechanism that may explain this benefit is regression of left ventricular hypertrophy (LVH); an …
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Pharmacometrics to characterize pharmacokinetics and optimize treatment in understudied populations
… adherence monitoring tool using enalapril, an angiotensin-converting enzyme inhibitor for hypertension and heart failure, in a small cohort of African heart failure patients, and characterizing pharmacokinetics of esomeprazole, a proton pump inhibitor for hyperacidity and being investigated for …
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A systematic review of outcomes associated with withholding or continuing angiotensinconverting enzyme inhibitors (ACE-I) and angiotensin receptor blockers (ARB) prior to noncardiac surgery
… surgery increasing numbers are taking either an angiotensin-converting enzyme inhibitor (ACE-I) or an angiotensin receptor blocker(ARB). The current recommendations whether to continue or withhold ACE-I and ARB in the perioperative period are conflicting. Previous metaanalyses have linked …
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Corneal fibrosis therapies and investigations in the canine corna in vitro
… safety and anti-fibrotic effects of the drugs, angiotensin-converting enzyme inhibitor (ACE-I) lisinopril and rho-kinase inhibitor (ROCK-I) fasudil, alone and in combination, on the canine cornea using an established in vitro model. Methods: To test the safety and efficacy of lisinopril and …
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Cardiovascular magnetic resonance characterisation of the phenotype of resistant uncontrolled hypertension
… a long-acting calcium channel blocker, an angiotensin converting enzyme inhibitor or angiotension receptor blocker and a diuretic. The prevalence of RH in South Africa is currently unknown, however, clinical reports suggest that it is not rare. Patients with RH are significantly predisposed …
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Magnetic resonance imaging studies of cardiac changes in diabetic and hypertensive rats
… streptozotocin-treated rats. The effects of the angiotensin-converting enzyme inhibitor captopril upon such changes were also investigated. Finally, the MRI methods were also used to characterize the corresponding right ventricular changes in the spontaneously hypertensive rats (SHR), also for …
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Central autonomic control in spontaneously hypertensive rats: a study on phasic phenomena during rapid-eye-movement sleep
… by means of a chronic treatment with an angiotensin converting enzyme inhibitor, the Enalapril maleate, from the age of four weeks to the end of the experiment. All rats were implanted with electrodes for electroencephalographic and electromyographic recordings and with an arterial …
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Pathophysiological role of aldosterone in cardiac remodelling after myocardial infarction
… that the use of eplerenone in addition to an angiotensin-converting enzyme inhibitor or angiotensin receptor blocker was well-tolerated. I also found an effect of eplerenone on two matrix metalloproteinases (MMPs) considered key enzymes in extracellular matrix turnover. Specifically, …