Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 8 of 8 for “"and cellular physiology"”.
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Beyond MICS: Determining the Role of Porin Production and β-Lactamase Expression in Resistance and Cellular Physiology of Klebsiella pneumoniae
… antibiotics through expression of β-lactamases and downregulation of outer membrane porins. However, the extent to which these mechanisms interplay in a resistant phenotype is not well understood. β-lactamase expression has long been presumed to have a previously unidentified fitness cost. In …
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Aneuploidy causes proteotoxic stress in Saccharomyces cerevisiae
… to date. How aneuploidy affects organismal and cellular physiology is only beginning to be understood. Aneuploidy also has a profound impact on human health; it is the leading cause of mental retardation and spontaneous abortions and a key characteristic of cancer, as more than 90% of all …
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C. elegans as a Platform for Multimodal Neural Data Integration
… levels of organization, creating methodological and conceptual gaps that hinder unified understanding of neural function. This thesis examines the nematode Caenorhabditis elegans as a platform for integrating diverse neural data modalities, offering a pathway to bridge these gaps. The …
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Role of NMDA in the Visual Working Memory of the Macaque Monkey
… role in mental disorders such as schizophrenia and therefore further investigations into the neural basis of this cognitive function may aid in the study of disease states where this cognitive function is defective. A likely neural correlate of working memory has been identified in the …
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Metabolic flux analysis and population heterogeneity in mammalian cell culture
Metabolic flux and population heterogeneity analysis were used to develop relations between mammalian cell physiology and specific culture environments and to formulate strategies for increasing cell culture performance. Mitochondrial characteristics associated with respiration, membrane potential, …
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The role of coordinated regulation and aromatic metabolites in activating the mar/sox/rob regulon of Escherichia coli
… genetic elements contained in transposons and plasmids. In contrast to this view, many bacterial species are equipped with intrinsic mechanisms to survive exposure to a wide variety of antimicrobial compounds. This form of resistance is mediated through regulated expression of efflux pump …
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Mitochondrial dysfunction in hereditary optic neuropathies
… can be caused by mutations in both mitochondrial and nuclear genomes. The poor knowledge of pathologic mechanism of these disorders has not allowed a real development of the “mitochondrial medicine”, that is currently limited to symptoms mitigation. Leber hereditary optic neuropathy (LHON) was the …
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"Effects of nonthermal plasma on prokaryotic and eukaryotic cells"
… pollution control, polymer science, food safety, and biomedicine. The capacity to harness highly charged particles and UV light created from electrified gases (also known as plasma) begs analysis of the product spectrum resulting from each gas or their combinations. The discharge profile of a …