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Showing 1 to 8 of 8 for “"ancestry informative markers"”.
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Ancestry Informative Markers Tailored to Hispanic Populations
… population; this makes an accurate panel of ancestry informative markers (AIMs) especially important for human identification. In Chapter 2, the Genomic Origins and Admixture in Latinos (GOAL) dataset containing 494,886 SNPs was used for SNP ascertainment. Utilizing a country attributable …
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The assessment of forensic molecular markers for skin colour in South Africans
… colour, and provide investigative leads. Several ancestry informative markers (AIMs) have previously been associated with human skin colour in mainly the European and North American population groups, while admixed populations are hardly studied. The present study aims to contribute towards this …
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Ancestralidade como fator de risco para hipotireoidismo: estudo da coorte ELSA-BRASIL
Introduction– Genomic ancestry refers to the genetic relationship between an individual and their ancestors, from whom they biologically descend. The self-reported ancestry of the Brazilian population is subject to important genomic divergence and there are sensitive markers capable of stratifying …
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The Association of Single Nucleotide Polymorphisms (SNPs) in the Nitric Oxide Synthase 1 Adaptor Protein Gene (NOS1AP) and the QT Interval Duration Across Race/Ethnicity in Adults Without Clinical Cardiovascular Disease
… group, using an additive model of inheritance. Ancestry informative markers (AIMs) were genotyped in MESA participants and principal components (PCs) using AIMs were used as additional covariates in accounting for population stratification (PS). Results: Associations between genotype and QT …
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Assessment of 13 Forensic Molecular Markers for skin colour in South Africa
Molecular phenotyping is the use of informative genetic variation to estimate appearance. This concept can be applied in a forensic context to predict the appearance of suspects or decayed deceased individuals, which would otherwise remain unidentifiable. This concept has importance in a local …
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IDENTIFYING GENES THAT CONTRIBUTE TO TYPE 2 DIABETES SUSCEPTIBILITY IN CAUCASIAN AND AFRICAN AMERICANS
… diabetic cases and 1054 controls. Sixty eight ancestry-informative markers (AIMs) were also genotyped to account for the impact of admixture on association results. Apart from TCF7L2 (rs7903146, Pa=1.59x10-6), we observed little evidence of association with T2DM in AAs. In fact, only rs9300039 …
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Application of autosomal INDELs as a forensic tool in Qatar
… Repeats (STRs) are the most commonly genetic markers used in forensic human identification. However, in some cases they are not able to yield complete profiles because of DNA degradation and/or inhibition. The STR profiling of the degraded/inhibited DNA samples can result in allelic drop-outs …
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Genetic ancestry and population health: elucidating the relative role of African genetic ancestry in cancer genomics and the broader implications for racial health disparities in cancer
… Among these groups, individuals of African ancestry, particularly African Americans, face some of the most severe outcomes, including higher incidence rates, delayed diagnoses, poorer prognoses, reduced survival, and less effective responses to treatment. While historical and systemic …