Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 13 of 13 for “"amphiphilic polymers"”.
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The use of novel poly(allylamine) based amphiphilic polymers for drug delivery.
Fourteen novel comb shaped amphiphilic polymers were successfully synthesised to determine the effect of polymer architecture on the potential of these amphiphilic polymers for hydrophobic drug delivery. Polyallylamine (PAA) was grafted with four different types of hydrophobic pendant groups …
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Cationic amphiphilic synthetic macromolecules with superior antibacterial activity
… design, synthesis, and development of synthetic amphiphilic macromolecules with antimicrobial activity and very low hemolytic impact. Synthetic amphiphilic polymers attack bacteria directly to rupture the cell membrane through electrostatic and hydrophobic interactions. However, the toxicity of …
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Development of polymer-coated nanoparticle imaging agents for diagnostic applications
… diagnostic applications. Low-molecular weight, amphiphilic polymers capable of noncovalent interactions with nanoparticle surface ligands and the aqueous environment were synthesized and characterized for use in nanoparticle coating applications. We demonstrate that the hydrophobic and …
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The investigation of interactions between single walled carbon nanotubes and flexible chain molecules
… in solution using a surfactant, and amphiphilic polymers of various types are frequently employed for this purpose. In addition to colloidal stability, such polymers can control surface adsorption, aggregation and in some instances, select particular diameters or chemical species for …
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Development and biophysical characterization of a hyaluronic acid – vitamin E conjugate as a subcutaneous delivery platform
… therapeutic efficacy. Nanogels, formed from amphiphilic polymers, combine the unique and tunable properties of hydrogels and nanoparticles into one drug delivery system and have the potential to drastically improve the clinical applicability of protein therapeutics delivered subcutaneously. …
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Surface functionalisation techniques for colloidal inorganic nanocrystals
… uses the hydrophobic interaction between an amphiphilic polymer and nanocrystal ligands to provide a foundation for growth of a silica layer. The coated nanocrystals are characterised using a wide range of techniques confirming that the presence and location of the silica shell. In Chapter 4, …
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Bioinspired soft matter self-assembly and its use in biomedical applications
… human body consists of a dynamic collection of polymers, colloids, and gels. Therefore, most biological matter is soft matter, and many biomedical products, such as 3D cell culture platforms or nanocarriers for drug and imaging agent delivery, often consist mostly of soft matter. Despite …
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Modification of Wood Fiber with Thermoplastics by Reactive Steam-Explosion
… in the appendices that relate to adsorption of amphiphilic polymers to the cellulose fiber surface, which is one hypothesis of fiber surface modification by co-steam-explosion. Microscopy studies revealed that PO melt viscosity was found to influence the degree of dispersion and uniformity of …
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Amphiphilic Poly(2-isopropyl-2-oxazoline)-block-poly(lactide) Nanoparticles as Drug Delivery Vehicles
… molecules to outline the potential of the amphiphilic block copolymers in drug delivery applications. To study the morphology of the nanoparticles, absorption and emission spectra of pyrene were measured in water dispersions of the nanoparticles at several concentrations. The obtained …
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A novel polyelectrolyte complex between amphiphilic poly (allyl amine) and sodium alginate.
Polyelectrolytes are charge-carrying polymers. When two oppositely-charged polyelectrolytes are combined in a solution favouring charge expression, a polyelectrolyte complex can result. These complexes have been shown to be useful in the field of drug delivery in general. Amphiphilic …
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Nanomicelles And Liposomes For Improving Drug Delivery of Small Molecules And siRNA Therapeutic Agents
… contained HA-ss-PLGA and Vitamin E TPGS amphiphilic polymers. Addition of RTV can inhibit P-gp and CYP3A4 mediated metabolism of PTX, thus increasing the intracellular levels of the chemotherapeutic drug. This can help in reversing MDR and sensitizing the cells towards PTX. In the second …
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Hybrid Devices : Morphology Control by Self-Assembly
… functional dyes as well as well-controlled polymers and blockcopolymers. In the first part, BODIPY (4,4-difluoro-4-bora-3a,4a-diaza-s-indacene) dyes were investigated which feature a broad absorption range up to the IR region accompanied by high extinction coefficients. These dyes were …
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Einstufen-Synthese und Charakterisierung amphiphiler Sternpolymere als multifunktionale assoziative Verdicker
… mehrfach hydrophob endmodifizierten hydrophilen Polymers die Struktur und Dynamik solcher Netzwerke beeinflusst. Die Synthese verzweigter Polymere auf PEG-Basis erfolgt mittels lebender ionischer Polymerisation und ist experimentell aufwändig. Das Einführen hydrophober Endgruppen erfordert …