Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 62 for “"amino acid metabolism"”.
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Amino Acid Metabolism in an Extremely Halophilic Bacterium
Made available in DSpace on 2014-12-09T22:04:10Z (GMT). No. of bitstreams: 1 6507093.pdf: 3420861 bytes, checksum: 6fa0927513809597d5aade6d0c0b435c (MD5) Previous issue date: 1965
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Modeling post absorptive amino acid metabolism in dairy cattle
… 1) update and evaluate predictions of essential amino acid (EAA) outflows from the rumen, 2) predict EAA use and release by the portal drained viscera (PDV) and liver (LIV) of dairy cows, 3) predict EAA use by the mammary (MAM) and non-splanchnic, non-mammary (OTH) tissues, and 4) predict milk …
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Branched-Chain Amino Acid Metabolism in the Neonatal Pig
Branched-chain amino acids (BCAA) are a group of essential amino acids consisting of leucine, isoleucine, and valine. Leucine, in particular, has signaling functions affecting protein and energy metabolism. Plasma leucine concentration is positively correlated with obesity and associated metabolic …
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Amino acid transporters & amino acid metabolism in Trypanosoma brucei brucei
… mediate the entry of drugs into the cell. Some amino acid transporters fulfil the criteria needed for successful exploitation of nutrient transport systems for drug delivery. The Trypanosoma brucei genomic database was screened to identify the full gene repertoire of amino acid transporters. …
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Mapping And Directing Branched-Chain Amino Acid Metabolism In Health And Insulin Resistance
… serum have identified changes in branched-chain amino acid (BCAA) levels as biomarkers of diabetes, heart failure, and some forms of cancer. However, the changes in BCAA metabolism in each of these cases, and even in the normal state, have remained elusive. Using novel heavy-isotope infusions, I …
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The Effect of Age and Sex on Chemotherapy-Induced Cachexia and Branched-Chain Amino Acid Metabolism
… causes appetite loss, fatigue, altered metabolism and decreased physical activity, all contributing to muscle tissue breakdown and cachexia. Decades of research into investigating interventions to mitigate the effects of cachexia have been unsuccessful. Even the use of nutritional …
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The Influence of Feeding Pattern on Protein and Amino Acid Metabolism in The Rat and The Pig
Made available in DSpace on 2014-12-09T14:29:05Z (GMT). No. of bitstreams: 1 6915367.pdf: 4569972 bytes, checksum: b6df4aed496fc1a55ea49609b72cfd18 (MD5) Previous issue date: 1969
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Heterozygote detection and genetic analysis of serum amino acid metabolism in Amish and non-Amish families with a phenylketonuric proband
This document only includes an excerpt of the corresponding thesis or dissertation. To request a digital scan of the full text, please contact the Ruth Lilly Medical Library's Interlibrary Loan Department (rlmlill@iu.edu).
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Amino Acid Balance and Imbalance in the Pig With Emphasis on Urea-Cycle Metabolism and Interorgan Amino Acid Transfers
Several experiments were conducted to investigate amino acid metabolism in pigs as affected by arginine deficiency, fasting and amino acid imbalances. Supplemental citrulline replaced arginine for growth in pigs fed arginine-deficient diets whereas ornithine supplementation was without effect. …
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Characterization of the Arabidopsis glutamine dumper1 mutant reveals connections between amino acid homeostasis and plant stress responses
Amino acids constitute the major organic form of transported nitrogen in plants, elements for protein synthesis, and precursors of many plant secondary metabolites, such as lignin, hormones, and flavonoids. Furthermore, amino acid metabolism lies at the crossroad of carbon and nitrogen metabolism. …
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Physiological response of bacillus licheniformis NCIMB 8874to oligosaccharide elicitors
… were mainly involved in energy generation, amino acid metabolism and stress responses. The addition of OG and MO to the cultures also altered the phosphorylation state of twelve proteins involved in energy generation, stress response and amino acid metabolism. Biochemical assays revealed …
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Investigation of growth and stress tolerance characteristics of Cronobacter spp.
… of mutants identified were associated with amino acid metabolism. The final section of this thesis identified genes involved in the tolerance of C. sakazakii to the milk derived antimicrobial peptide, Lactoferricin B (Lfcin B). This was achieved by creating a transposon mutagenesis library …
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Nutrient and Stress-Induced Mitochondrial Hyperfusion Regulates Cell Death Pathways
… to avoid apoptosis. Importantly, in response to amino acid starvation, mitochondria have been reported to undergo fusion to form elongated structures that avoid degradation via mitophagy. Here, we aimed to study the signals controlling nutrient-dependent mitochondrial fusion and we attempted to …
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Novel Functions of the Transcription Factor Aryl Hydrocarbon Receptor (AHR) and Its Tryptophan-Derived Ligands in Cancer Cells
… The role of MYC in regulating tryptophan (Trp) metabolism was investigated in colon and liver cancer cells using high-performance liquid chromatography-tandem mass spectrometry (LC-MS/MS). Our findings reveal that MYC enhances the intracellular levels of Trp and its metabolites in the kynurenine …
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Regulation and roles of nutrient-dependent mitochondrial fusion
… shown that mitochondria undergo fusion during amino acid starvation-induced autophagy. This mitochondrial response has been proposed to be regulated by MTORC1, a key regulator of nutrient-sensing signalling pathway. However, the mechanism linking MTORC1 and nutrient sensing to mitochondrial …
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Molecular and transcriptomic studies of quorum sensing in Chromobacterium subtsugae
… These genes are predicted to play a role in amino acid metabolism, motility, conjugation, antibiotic resistance, and many more. Our results provide evidence for a novel function of the quorum sensing system. C. subtusgae can sense the presence of competitors by through non-cognate AHL …
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Nutritional modeling of bacterial infections : physiology and metabolism of Pseudomonas aeruginosa during growth in cystic fibrosis sputum
… P. aeruginosa up-regulates genes important for amino acid and lactate metabolism during growth in CF sputum as compared to a laboratory medium. P. aeruginosa also demonstrates enhanced production of the cell-cell communication signal 2-heptyl-3-hydroxy-4-quinolone (the Pseudomonas quinolone …
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Investigating and exploiting fungal natural products in Aspergillus spp.
… in several cellular processes, especially metabolism. Two putative S-adenosylmethionine (SAM)-dependent methyltransferases showed de novo abundance under GT conditions. In addition an increase in abundance of proteins involved in the methionine cycle was also observed. Analysis of …
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