Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 19 of 19 for “"alternatives to antibiotics"”.
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A CONTRIBUTION TO THE STUDY OF BIOCONTROL AGENTS APITHERAPY AND OTHER POTENTIAL ALTERNATIVES TO ANTIBIOTICS
We are living in what has been termed the “post antibiotics era’ where the emergence of multidrug-resistant pathogen strains is rapidly growing and where the introduction of and the development of novel antimicrobial agents, which are effective against these pathogens has declined significantly. As …
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Evaluation of antibacterial activity of plant-food by-products and their potential application in livestock animals
Overuse and improper use of antibiotics, especially in food animals for growth promotion and disease prevention, promote the development of antibiotic resistance, which poses a severe threat to health of humans and animals. To slow the pace of antibiotic resistance and preserve the efficacy of …
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The effect of tylosin exposure or exclusion on liver abscess prevalence, fecal pathogen populations, and the microflora of finished beef products from feedlot cattle
There is great pressure to reduce use of, and find alternatives to, antibiotics in animal production. More than 70% of feedlot cattle in 1000+ head lots are currently exposed to tylosin phosphate, a macrolide antibiotic used for the reduction and prevention of liver abscesses. As such, its …
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The discovery of a bioactive peptide, QUB-1957, from the defensive skin secretion of the Chinese piebald odorous frog, Odorrana schmackeri
… have developed drug resistance, which has led to the search for new alternatives to antibiotics as one of the hottest topics nowadays. The frog skin secretion may be a potential source where increasing numbers of antimicrobial peptides (AMPs) have been discovered.<br/><br/>In this study, we …
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Benchmarking Biological Indices of Commercial Broiler Chickens Reared on Conventional and Alternative Gut Health Management Programs
… has been phasing out prophylactic use of antibiotics in broiler chicken production thereby mandating the industry to contend with less reliance on the use of antibiotics. Under current Canadian regulations, the majority of commercial broiler chickens are reared on one of three gut health …
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Exploring the Pharmacological Potential of Bioactive Peptides in Amphibians and Plants: from Identification to Rational Design
… molecular cloning of a novel trypsin inhibitor (as the probable alleleic variants TKTI-2 and TKTI-3) from the dried root of Trichosanthes kirilowii indicates that mRNA can persist in decoction pieces and so could present a viable option for the molecular cloning from other TCMs.<br/><br/>It …
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The Influence of Prebiotics, Probiotics, and Exposure to an Opportunistic Pathogen on the Intestinal Microbiome of White Shrimp (Litopenaeus vannamei)
Prebiotics and probiotics, proposed alternatives to antibiotics in shrimp aquaculture, are reported to improve growth parameters, promote disease resistance, and influence the gut microbial community. This study aimed to investigate the influence of prebiotic- or probiotic-coated feed and/or …
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Proteomic Characterization of Eggshell Membranes and Their Effect on Poultry Physiology and Immunity
<p>The use of antibiotics in poultry growth and disease control has led to antibiotics resistant problem in human beings, which is a big concern among consumers. With the necessity for judicious use of antibiotics in poultry production, alternative strategies to improve disease resistance in …
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The Noncontractile Phage Tail-like Bacterial Killing Nanomachines – Characterizing the Specificity Determinants of the F-Pyocins of Pseudomonas aeruginosa
… bacterial strains poses an enormous threat to our collective human existence; hence, there is a dire need to search for alternatives to current antibiotic treatment options. In this work, I characterized the non-contractile phage tail-like entities called F-pyocins. F-pyocins are high …
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Effects of Direct-Fed Microbial Products, Butyrate, and Botanicals on Performance and Health of Broilers Raised on Used Pine Shaving Litter
Two experiments were conducted to determine the effects of various alternatives to antibiotics in broilers grown on used litter on performance, intestinal lesion scores, body composition, and cecal volatile fatty acid (VFA) concentrations. The first experiment used a corn-soybean meal based basal …
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Potential of bacteriocin producing bacteria to control VRE infection
… that antibiotic resistant pathogens cause up to 700,000 deaths each year. The Centre for Disease Control ranks vancomycin resistant enterococci as a serious threat. They estimate that in 2017 alone there were at least 54,500 cases in hospitalized patients. The rise of antibiotic resistance …
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Knowledge, attitudes and perceptions of antibiotic use and antibiotic resistance among private sector patients and prescribers in South Africa
Antibiotic resistance (ABR), alternately referred to as antimicrobial resistance, has been labelled as the next big global health crisis. If current levels of ABR continue along the same trajectories, by 2050 ABR will cost the lives of 10 million people a year, ABR cannot be stopped but it can be …
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Characterisation of novel bacteriocins from canine sources
… for bacteriocins as an alternative or adjunct to traditional antibiotics. More specifically, this thesis explores the class Ia bacteriocins termed lantibiotics, and the identification and characterisation of novel bacteriocins from canine sources. Chapter 1 focuses on the current knowledge …
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Immunomodulatory effects of whole yeast cells and capsicum in weanling pigs challenged with pathogenic escherichia coli
Post-weaning diarrhea, caused by enterotoxigenic Escherichia coli, is one of the most common causes of mortality and morbidity in commercial pig production. With recent global concern over antibiotic resistance, the development of nutritional technologies to support animal health during times of …
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Characterization of a salmonella phage using omic tools and mathematical models to predict host-phage interaction
The increasing resistance of pathogenic bacteria to antibiotics in recent years has become a major problem in controlling infections in animals and humans. Salmonella enterica, which causes human food poisoning worldwide, is one of the most problematic bacteria with significant incidence in …
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Effects of phytogenics on intestinal pathogenic bacteria and microbiota of non-ruminants
… bacteria worldwide pose a significant threat to human and animal health. The recommendations in the WHO’s global action plan were to phase out and research alternatives to using antibiotics in animal farming. This study aims to identify natural plant supplements that can be used in animal …
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The effects of a yeast probiotic, saccharomyces cerevisiae boulardii, on common sow stressors and their effect on maternal-fetal programming
To date, antibiotics have been widely used in conventional animal medicine, as they are non-selective, as well as effective in killing pathogenic bacteria (Conly and Johnston, 2004). However, there is mounting concern over the increasing emergence of antibiotic-resistant bacteria due to the use of …
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Investigation of Biofilm Development by Antibiotic Resistant Urinary Tract Infection Pathogens and Evaluation of the Antimicrobial Activity of Natural Products on Carbapenem-Resistant Escherichia coli IMP and Klebsiella pneumoniae NDM-1.
… biology behind the ability of these pathogens to form biofilms is crucial to the treatment of the infections caused by these pathogenic bacterial strains. Resistance to carbapenems is of major concern because they are typically used as a treatment of last resort for infections associated with …
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Improving Nutrient Utilization and Growth in Dairy Heifers
… (ADG), but consume less starter which can lead to stress during weaning and reduced rumen development. The greater amount of CP being fed to preweaned calves may alter their nitrogen (N) balance and body composition. Deuterium oxide (D2O) dilution methods have been used for assessment of body …