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Showing 1 to 2 of 2 for “"alternative-NHEJ"”.

  1. Pathways of NHEJ at Dysfunctional Telomeres and Their Resolution

    Karssemeijer, Roos Anna

    … the decision between non-homologous endjoining (NHEJ) and homologous recombination (HR). Telomeres lacking the shelterin protein TRF2 have proven a versatile system for studying 53BP1 in DSB repair since 53BP1 protects dysfunctional telomeres from resection and promotes their mobility. Analysis …

    rockefeller Repository record

  2. DNA repair proteins Metnase and PARP1 regulate DNA integration

    Nie, Jingyi, author, Nickoloff, Jac A., advisor, Bailey, Susan M., committee member, Liber, Howard L., committee member, Chen, Chaoping, committee memberColorado State University. Libraries2015

    … (HR) and non-homologous end joining (NHEJ). In mammalian cells, NHEJ occurs more frequently than HR, possibly explains why random integration is more efficient than homology-directed integration or gene targeting. Proteins function in DSB repair pathways often engage in DNA …

    colostate Repository record