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Showing 1 to 4 of 4 for “"alternative carbon metabolism"”.
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Regulation of Alternative Carbon Metabolism In Candida Albicans
… reorganization activating genes involved in alternative carbon metabolism, including the glyoxylate cycle, β-oxidation and gluconeogenesis. Mutations in key enzymes such as ICL1 (glyoxylate cycle) and FOX2 (fatty acid β-oxidation) revealed that alternative carbon metabolic pathways are …
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Characterization of The Ato Gene Family In Alternative Carbon Metabolism
… release (Ammonia Transport Outward) and acetate metabolism. I hypothesized that the Ato proteins are important effectors of the pH change <em>in vitro</em> and in macrophages. Deletion of one of the 10 homologs, <em>ATO5, </em>or the over-expression of a dominant negative <em>ATO1<sup>G53D</sup> …
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Regulation of The Candida Albicans Arginine Biosynthetic Pathway
… results primarily in the activation of alternative carbon metabolism pathways suggesting that the pathogen is exposed to a glucose poor environment. Changes in amino acid metabolism are not observed, with the only exception of arginine biosynthesis. The strong upregulation of the …
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Alternative Carbon Utilization As A Virulence Determinant For Candida Albicans
… to the macrophage phagosome by upregulating alternative carbon utilization processes. The utilization of three alternative carbon sources particularly contribute to <em>C. albicans </em>pathogenesis: carboxylic acids, amino acids, and <em>N</em>-acetylglucosamine. Studied individually, …