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Showing 1 to 1 of 1 for “"alpha-dicarbonyl"”.
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Loss of function of Gene X protects against α-dicarbonyl stress through the skn-1 pathway in C. elegans
… of highly oxidative byproducts produced from α-dicarbonyl compounds (α-dcs), which are highly reactive molecules that bind indiscriminately to protein and DNA and, are regulated by a conserved glyoxalase system (<em>GLO1</em> and <em>DJ-1</em>) in humans. Utilizing the conserved glyoxalase …