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Showing 1 to 4 of 4 for “"alpha-MSH"”.

  1. Interferon-gamma suppresses melanogenesis in B16 melanoma cells and primary human melanocytes

    … primary human melanocytes, I demonstrated that alpha-MSH induced tyrosinase expression and activity and TRP-1, TRP-2 expression were suppressed by IFN-γ, which resulted from the inhibition of MITF expression, upstream molecule of tyrosinase. Moreover, the inhibitory effects on MITF expression by …

    ajou Repository record for Interferon-gamma suppresses melanogenesis in B16 melanoma cells and primary human melanocytes (opens in a new tab)

  2. Analyzing the Interactions Between Xenopus tropicalis MC2R, MC5R, and the MRAPs: Modeling the Regulation of Frog Interrenal Cells

    … the receptors are stimulated with ACTH, or apha-MSH. Expression of these four genes in the frog interrenal was verified through RT-PCR. Then CHO-K1 cells were transfected with plasmid constructs containing <em>X. tropicalis</em> MC2R, MC5R, MRAP2, and a mouse MRAP, and stimulated with ACTH or …

    denver Repository record for Analyzing the Interactions Between Xenopus tropicalis MC2R, MC5R, and the MRAPs: Modeling the Regulation of Frog Interrenal Cells (opens in a new tab)