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Showing 1 to 4 of 4 for “"alpha-1-antitrypsin deficiency"”.

  1. Exacerbations, health status and sibling pair comparisons in severe Alpha-1-Antitrypsin Deficiency

    Alpha-1-Antitrypsin Deficiency (AATD) is a risk factor for the development of early-onset emphysema and airflow obstruction. The current work defines exacerbations, lung function and health status in these patients including sibling pairs. Exacerbations occur commonly in AATD and are associated …

    birmingham Repository record for Exacerbations, health status and sibling pair comparisons in severe Alpha-1-Antitrypsin Deficiency (opens in a new tab)

  2. The role of genetic and environmental variation in the respiratory phenotype of alpha 1 antitrypsin deficiency

    Alpha 1 antitrypsin deficiency (AATD) is the only established genetic predisposition to chronic obstructive pulmonary disease (COPD). The development of COPD in AATD is highly variable, probably relating to complex interactions between multiple genetic and environmental factors. This thesis will …

    birmingham Repository record for The role of genetic and environmental variation in the respiratory phenotype of alpha 1 antitrypsin deficiency (opens in a new tab)