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Showing 1 to 13 of 13 for “"allyl isothiocyanate"”.
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GENETIC DISSECTION OF AVERSION TO ALLYL ISOTHIOCYANATE IN Drosophila melanogaster
… responds to many electrophiles, including allyl isothiocyanate (AITC). Drosophila have four homologs to the mammalian TRPA1: dTRPA1, painless, pyrexia, and water witch. dTRPA1 and painless are thought to play a role in the behavioral aversion to AITC, however the role of painless is …
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Allyl isothiocyanate reduces Salmonella enterica Michigan and Listeria monocytogenes on the surface of whole cantaloupe (Cucumis melo L.)
… attachment. This research evaluates the use of allyl isothiocyanate (AITC; a natural antimicrobial) to reduce populations of S. enterica Michigan and L. monocytogenes on the surface of cantaloupe. Fifty μl of S. Michigan or L. monocytogenes was inoculated onto whole ‗Athena‘ or ‗Hales Best …
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Use of Extraction Technologies in Food Safety Studies
… to identify and quantify the flavor component allyl isothiocyanate (AITC) and related compounds in horseradish products. Solvent extraction, headspace sampling, and HS-SPME were compared, and HS-SPME gave acceptable accuracy and precision for the quantification of AITC and related compounds in …
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Eisenia hortensis Detects Chemesthetic Irritants through TRP Channels
… sampling method which expels earthworms with allyl isothiocyanate, a common Transient Receptor Potential 1 (TRPA1) channel agonist, we hypothesized that earthworms possess TRPA1-like channels. We examined whether the earthworm Eisenia hortensis possesses TRPA1-like channels, as well as other …
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Synthesis of exo-affinity labeling agents of protein tyrosine phosphatase non-receptor type 1
… towards new derivatives of Tirapazamine. Allyl isothiocyanate (AITC) is a phytochemical that can be found in cruciferous vegetables and has received interest due to beneficial health effects. During our analyses of AITC towards inactivation of PTP1B we noticed the surprising absence of the …
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Chemesthesis in the Earthworm, Lumbricus terrestris: The search for TRP Channels
… could have deleterious effects on plant growth. Allyl isothiocyanate, a prototypical TRPA1 agonist, has been used as an expellant for sampling earthworms, suggesting that earthworms possess TRPA1 channels. We began the search for TRPA1-like channels in earthworms using electrophysiological, …
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Female-Specific Mechanisms of Nociplastic Pain in Murine Model
… mechanistic player. In gonad-intact females, allyl isothiocyanate (AITC)-sensitive afferents at the previously injured area maintained the nociplastic pain state; these afferents spontaneously at a higher frequency and had a decreased mechanical threshold compared to control or acute …
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Identification of Volatile Compounds Contributing to the Aroma of Pennycress and Camelina Seeds and Protein Extracts
… intense odor were sinigrin degradation products (allyl isothiocyanate) and other sulfur-containing volatile compounds that produced a pungent garlic or radish odor. The compounds that produced an intense odor in the defatted meal of pennycress were similar to the seeds, but also contained …
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Evaluation of the Functional Roles of TRPA1 Homologs, Painless and dTRPA1, in Chemical Nociception in Drosophila
… in the behavioral aversion to the compound, allyl isothiocyanate, is disagreed upon. We have analyzed the behavioral phenotypes of <italic>painless</italic> and <italic>dTRPA1</italic> mutants using the proboscis extension reflex (PER) and two-choice capillary feeding assays, both of which …
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Digestive metabolism of glucosinolates: a novel approach using urinary markers for estimating the release of glucosinolate breakdown products in the gastro-intestinal tract of mammals.
… a range of metabolites including beneficial isothiocyanates. Little is known about the fate of glucosinolates after their ingestion. Using urinary end-products of metabolism as markers, measurement of the production of isothiocyanates in the digestive tract of monogastric animals has been …
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The role of foliar glucosinolates in host plant resistance of oilseed rape and mustard to the Bertha armyworm and the diamondback moth
… were negatively correlated to concentrations of isothiocyanate-releasing glucosinolates. In feeding tests with pure compounds in meridic diets, sinigrin and its metabolite, allyl isothiocyanate inhibited growth in a dose-dependent manner. No effects were observed with indole-3-carbinol, the …
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MODULATION OF SYNAPTIC TRANSMISSION AT THE NUCLEUS TRACTUS SOLITARIUS
… Administration of capsaicin (TRPV1 agonist) and allyl isothiocyanate (AITC, TRPA1 agonist) both increased the frequency of s/mEPSCs without affecting spontaneous and miniature inhibitory postsynaptic currents (s/mIPSCs). Next, the modulation of TRPV1- and TRPA1-induced responses by utilizing a …
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Improving the health benefits of broccoli through myrosinase maintenance
… an intermediate that breaks down to form the isothiocyanate SF. Importantly, when broccoli is crushed/chewed before swallowing by the consumer, the same process takes place as long as the isothiocyanate precursors are present. When broccoli is processed commercially for freezing, it undergoes …