Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 82 for “"allograft"”.
-
Humoral alloimmunity in cardiac allograft rejection
Although the short-term outcomes of solid allograft survival have improved substantially over the last few decades, there has been no significant improvement in long-term survival of solid allografts. This thesis presents the initial characterisation of alloantibody mediated rejection in a murine …
-
Destruction of Corneal Nerves Promotes Corneal Allograft Rejection
… contributes to the 90% success rate of corneal allografts without the need for histocompatibility matching and use of systemic immunosuppressive therapy. However, when one or more parameters that contribute to immune privilege are broken, the cornel allograft becomes vulnerable to the immune …
-
Endomyocardial biopsy diagnosis of acute cardiac allograft rejection
… that may be used to diagnose acute cardiac allograft rejection; (ii) to review the use of the bioptome in sampling the donor heart endomyocardium; (iii) to review the light microscopic and histological grading of acute cardiac rejection; (iv) to characterise the mononuclear populations in …
-
Angiogenesis in human parathyroid disease and chronic allograft nephropathy
Angiogenesis in parathyroid disease and association with VEGF
-
Osteochondral allograft preservation in a serum-free chemically-defined media
… the tissue have been developed. Osteochondral allografts (OCAs) allow the transplantation of whole cartilage tissue into a defect with viable cells, or chondrocytes that will maintain the cartilage matrix. Fresh OCAs have demonstrated greater than 75% clinical success in the treatment of …
-
CD4 T cell allorecognition pathways in acute and chronic allograft rejection
… restricted allopeptide) pathways make to allograft rejection remains incompletely understood. In this thesis, murine models of heterotopic cardiac transplantation have been utilised to analyse these pathways. The key findings of this work are as follows: 1) If able to evade NK cell …
-
Application of a Periosteum-bone Allograft for Healing of Segmental Bone Defects
Whole bone allografts or autografts are commonly applied surgically to repair approximately 2.2 million segmental bone defects annually caused by trauma or bone tumor resection worldwide.[1] However, about 15-40% of these cases result in unsuccessful healing because of a persistent gap or nonunion …
-
Allograft bone in hip revision: the effect of locally applied pharmacological treatment.
… bone loss has been the impaction technique. Allograft bone is morsellised and impacted into the defect before a prosthesis is inserted. Mechanically, the allograft bone immediately contributes to prosthetic stability. Biologically, the graft triggers an inflammatory response with ingrowth of …
-
Combination of a cortical allograft with a cancellous autograft in the canine tibia
Photocopy of typescript.
-
Combination of a cortical allograft with a cancellous autograft in the canine tibia
Photocopy of typescript.
-
Mechanical and biological augmentation of allograft and synthetic graft in impaction bone grafting
… mechanical properties of HBMSC seeded onto<br/>allograft or PDLLA were compared to allograft or PDLLA alone in vitro.<br/><br/>Part II: Evidence of biocompatibility, neovascularisation and new bone formation in<br/>impacted allograft and PDLLA scaffolds seeded with HBMSC, in vivo was …
-
Characteristics of Donor-Specific anti-HLA Antibodies (DSA) Impacting different Renal Allograft Outcomes
… transplantation that significantly affects the allograft survival. Complement fixation of Donor specific anti-HLA antibodies is the hallmark of AMR. Different methods have been developed to detect harmful DSAs. However, not all DSAs have the same detrimental effect, as different antibody …
-
Cytokine Gene Expressions of Peripheral Blood Mononuclear Cells in Acute Renal Allograft Rejection
… advances in immunosuppressive drugs, renal allograft rejection remains the main crucial determinant of the long term graft function and outcome. To solve this problem, there have been many efforts to explore the participation of cytokines and related gene expression in allograft rejection. …
-
Raman Spectroscopic Modeling Of T- Lymphocyte Activation And Detection Of Acute Renal Allograft Rejection
… ACTIVATION AND DETECTION OF ACUTE RENAL ALLOGRAFT REJECTION</p> <p>By</p> <p><strong>KRISTIAN L. BROWN</strong></p> <p>2010</p> <p>Advisor: Gregory Auner, PhD</p> <p>Major: Biomedical Engineering</p> <p>Degree: Doctor of Philosophy</p> <p>Despite the advances made in the area of kidney …
-
Radiologic, Histologic and Functional Evaluation after Implantation of Cultured Trachea Allograft : in vivo study
BACKGROUND: Commonly known as praying about how hard of a reconstruction, cartilage grafts, anastomosis country EP and the glass plate or Sophie. The sum of the areas of narrowing it after removing the door if possible, all the way to the ideal treatment in patients with anastomosis hard liquor, …
-
Renal allograft biopsies at Groote Schuur Hospital: a histopathologic descriptive study with molecular insights
Background: Kidney transplantation is the definitive treatment for end-stage kidney disease. Immune-mediated rejection remains a barrier to success. It is diagnosed through the Banff classification, which incorporates histopathology and biomarkers (C4d/donor specific antibodies (DSA)). In …
-
Healing Following Periodontal Reconstructive Surgery : Surgical Implantation of a Collagen Matrix or Demineralized Freeze-dried Bone Allograft
… matrix or demineralized freeze-dried bone allograft (DFDBA) was evaluated in a preclinical (collagen) and a clinical (DFDB A) study.</p> <p>Contralateral periodontal fenestration defects in 7 beagle dogs were used to evaluate the effect of a collagen matrix on periodontal healing. The …
Page 1 of 5