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Showing 1 to 7 of 7 for “"allogeneic stem cell transplantation"”.
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Donor lymphocyte infusion after allogeneic stem cell transplantation in children
… and bone marrow failure syndrome following allogeneic hematopoietic stem cell transplantation (allo HSCT). However, DLI is limited by the development of graft-versus-host disease (GVHD)and marrow aplasia, and the efficacy of DLIis not defined in children. So we evaluate DLI for last decade, …
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Tumor immune escape in allogeneic stem cell transplantation: Releasing the brake on graft-versus-tumor immunity
Contains fulltext : 101020.pdf (Publisher’s version ) (Open Access)
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Stimulation of donor t-cells with leukemic blast-loaded dendritic cells for the generation of leukemia-specific immunity in the context of allogeneic stem cell transplantation
… with chemotherapy and in some cases also by stem cell transplantation (SCT). The relapse rates are high, and long-term disease-free survival occurs in less than half of the AML patients. The curative potential of the allogeneic SCT can be explained by the pre-transplant chemo/radiotherapy in …
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Investigating The Role of Il-10 Producing Nkt Cells In Prevention of Graft Versus Host Disease
… treatment for hematologic malignancies is allogeneic stem cell transplantation (ASCT), in which the patient’s immune system is replaced with that of a healthy donor. This can lead to cure through the graft versus leukemia (GVL) effect but can also cause graft versus host disease (GVHD), …
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Natural and Exogenous Genome Editing In Wiskott-Aldrich Syndrome Patient Cells
… (WASp), exclusively expressed in hematopoietic cells and required for proper platelet production and lymphoid cell function. Approximately 11% of patients with WAS exhibit a phenomenon called Somatic Revertant Mosaicism which is characterized by the presence of lymphocytes which naturally revert …
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Changes in peripheral B cell subsets under immunosuppressive therapy
Normal homeostasis of the immune system is critical for the maintenance of immunological tolerance and immunocompetence. Failure of self-tolerance results in autoimmune reactions which may progress to chronic autoimmune diseases. B cells play an important role in the pathogenesis of autoimmune …