Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 126 for “"allergen"”.
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Allergen specific immunoglobulins during pregnancy.
… serum concentration of IgE and IgG4 (total and allergen specific taking Timothy grass pollen as the model allergen) have been investigated prospectively during and after pregnancy in healthy women and women suffering from allergic rhinitis. The results show that the total serum IgG concentration …
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Allergen Sensitization and Immunomodulation By Synthetic Ligands, Pul-042, In An Allergen-Induced Asthma Murine Model
<p>Allergen-induced asthma is the leading form of asthma and a chronic condition worldwide. Common allergens are known to contribute to the pathogenesis of this disease. Murine models of allergic asthma have mostly used an intraperitoneal route of sensitization (not airway) to study this disease. …
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Nuclear magnetic resonance structural studies of allergen protein
Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Chemistry, 1994.
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The effect of the Food Allergen Labeling and Consumer Protection Act (FALCPA) on the accidental food allergen ingestion rate in adults with self-reported food allergies
<p>Background: The Food Allergen Labeling and Consumer Protection Act (FALCPA) recently required bolded allergens or “contains” statements on food product labels. Very few U.S. studies have looked at the accidental food allergen ingestion rate in adults. Since the emotional and medical costs of …
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Home Environments and Allergen Avoidance Practices in a Hot, Humid Climate
… home conditions, housing satisfactions, and allergen avoidance practices of people with allergic rhinitis, focusing on female patients who lived in an urban area in a hot, humid climate. The Morris and Winter theory of housing adjustment provides a theoretical base for this study. Nine …
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Optimizing The Nasal Allergen Challenge Model For The Study Of Allergic Rhinitis
… Investigator Collaborative (AR-CIC) uses a Nasal Allergen Challenge (NAC) model to study the pathophysiology of AR and provides proof of concept for novel therapeutics. The NAC model needs to ensure optimal participant qualification, allergen challenge, clinical symptoms capture and biological …
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Cloning, Expression, and Characterization of Ara h 3, a Major Peanut Allergen
… may be obtained by studying the structural and allergenic properties of individual allergens and the changes that occur due to food processing. In this study, the basic and acidic subunits of Ara h 3 were cloned, expressed, and purified, and compared with each other and with the native Ara h 3 …
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Improving Food Allergen Management in Small Food Service Businesses serving Loose Food
Food allergens, a concern for an increasing number of people, are common food ingredients found in most kitchens. For the majority of the population these ingredients are harmless yet for about 2% of the global adult population, these ingredients pose a health risk and at times could also be life …
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Expanding Allergen-specific Tr-1 CD4+ T cells to treat Allergic Asthma
… and found that the pMHC-NP therapy triggers allergen-specific Tr-1 cell formation and expansion that can suppress inflammation, promoting the resolution of airways hyper-responsiveness and airway remodeling. Asthma-relevant pMHC class II-coated NPs may therefore represent a viable alternative …
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Allergen wheal area during early childhood predicts allergic rhinitis phenotypes at age four
… itching, and sneezing in response to allergen exposure. Allergic rhinitis is common in childhood, affecting 42% of six year old children, and is associated with an increased risk of asthma. Thus, determining early childhood risk factors may be important for not only AR, but also …
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Allergen-induced change in airway responsiveness to direct and indirect stimuli in mild atopic asthmatics
… like MCh tends to increase following exposure to allergen but the response to mannitol an indirect stimuli, is not known. Furthermore, the provocative concentration causing a 20% decrease in Forced Expiratory Volume in one second (FEV1) for adenosine 5’ monophosphate (AMP) correlates better to …
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The Role of ASK1 in Allergen-mediated Mast Cell Signaling and Activation-dependent Inflammatory Responses
… at alarming rates and identifying key targets in allergen-induced mast cell-mediated inflammation is crucial for therapeutic development. Apoptosis signal-regulating kinase 1 (ASK1) is a mitogen-activated protein kinase (MAPK) that is involved in various cellular responses, including oxidative …
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Characterizing the Innate Immune Response of Human Airway Cells to the Unique Fungal Allergen Alt a 1
… innate immunomodulatory activities of the major allergen Alt a 1, from the ubiquitous airborne fungus, Alternaria alternata. In several studies, 90-100% of allergic patients who are sensitized to Alternaria, have Alt a 1 specific IgE antibodies indicating that it is a major and clinically …
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Oligomers of beta-L-arabinosides of hydroxyproline : synthesis of the carbohydrate epitope of the Art v 1 allergen
… The chemical structure of Art v 1, the major allergen of mugwort, has been elucidated. A notable motif in Art v 1 – characterized by clusters of contiguous â-arabinosides of hydroxyproline – was found to be a key recognition element for antibodies generated in response to the natural protein. …
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The Role of Alternaria and its Major Allergen, Alt a 1, in the Pathogenesis of Allergic Airway Disorders
… previously by several groups as the major allergen secreted by A. alternata, due to its IgE-specific reactivity with sera from atopic patients. Despite the well-documented clinical importance of Alternaria and its major allergen, little knowledge exists regarding their role and interaction …
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Struktur, Funktion und Allergenität Bet v 1-homologer Proteine: Das Allergen Gly m 4 und das Enzym Norcoclaurin-Synthase
… Nahrungsmittelallergien bei Erwachsenen durch allergene Proteine aus der Bet v 1-Familie ausgelöst, die nach dem Hauptbirkenpollenallergen benannt ist. Die Bet v 1-Familie wird in die Klasse 10 der pathogenesis-related proteins (PR10-Proteine) eingeordnet. Die PR10-Proteine spielen eine Rolle …
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