Global ETD Search
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Showing 1 to 1 of 1 for “"allele-specific RNAi"”.
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Molecular Genetic Analysis of Spinocerebellar Ataxia Type 7 and a Further Study on the RNA Interference Analysis
… which encodes Ataxin-7 protein. Normal ATXN7 alleles contain 4-35 CAG repeats. Expansion of CAG repeat in the mutant allele ranges from 36 to 460, with repeat length inversely correlated to the age of disease onset. However intermediate size alleles (having 28-35 CAG repeats) can be converted …