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Showing 1 to 1 of 1 for “"airways hydration"”.
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Channel activating proteases: molecular targets for correction of sodium channel dysfunction in cystic fibrosis airways disease
… to increased Na+ absorption which contributes to airways dehydration, thickened mucus, impaired mucociliary clearance and is thought to be a major contributor to the pathogenesis of lung disease. Previous work has shown that QUB-TL1, an active site directed inhibitor of trypsin and trypsin-like …