Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"airway eosinophilia"”.
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Neurokinin-1 antagonism as a novel treatment for feline asthma : investigation of the role of substance p in airflow limitation and airway inflammation
… and/or episodic respiratory distress induced by airway hyperresponsiveness (AHR), airway eosinophilia, and airway remodeling. Homeostasis in the lung is partially maintained by the neuroimmune axis, where cross-talk between these systems is mediated via cytokines, neuropeptides and their …
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Stem Cell and Biological Interventions to treat Allergic Airway Disease
… immune modulation with a particular focus on airway inflammation and allergic pathogenesis. This was probed in a model of pathogen driven immunomodulation (B. pertussis), and two models of therapeutic intervention namely immunisation (attenuated B. pertussis, BPZE1) or using a candidate cell …
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Allergen Sensitization and Immunomodulation By Synthetic Ligands, Pul-042, In An Allergen-Induced Asthma Murine Model
… an intraperitoneal route of sensitization (not airway) to study this disease. Allergic asthma pathophysiology involves the activation of T<sub>H</sub>2-specific cells, which triggers production of IgE antibodies, the up-regulation of T<sub>H</sub>2-specific cytokines (<em>i.e. </em>IL-4, IL-5, …
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Airway inflammation, diagnosis, perception of asthma, and sputum zinc levels in a community cohort.
… (IS), an established research tool to measure airway inflammation (AI), is normally confined to specialised institutions and selected populations with airway disease, especially asthma. This thesis examines the role of IS in the diagnosis of asthma in a community. The first study explores the …
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Functional Responses of Lung Dendritic Cell Subsets in Flt3 Ligand-Induced Immunomodulation in Allergic Asthma
Asthma is an inflammatory airway disease characterized by airway eosinophilia, airway obstruction due to an increased mucus production by goblet cells, airway remodeling, and airway hyperresponsiveness (AHR) to a variety of stimuli. In allergic airway inflammation, dendritic cells (DC) deliver …