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Showing 1 to 1 of 1 for “"agonists targeting S1P5"”.

  1. Developing a selective sphingosine-1-phosphate-5 (s1p5) radiotracer to image oligodendrocytes using preclinical positron emission tomography (PET)

    … ligands target the sphingosine-1-phosphate-5 (S1P5) receptor as a potential marker of oligodendrocyte function with PET. The ligands selected (TEFM180 and TEFM78) were developed from a drug development library of agonists targeting S1P5 that had shown high affinity and selectivity for their …

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