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Showing 1 to 2 of 2 for “"agonists interaction"”.

  1. Defining Novel Clusters of PPAR gamma Partial Agonists for Virtual Screening

    … mellitus (T2D). Thiazolidinediones (TZDs) are agonists of PPARγ which have an insulin sensitizing effect, and are therefore used as a treatment for T2D. However, TZDs cause negative side effects in patients, such as weight gain, edema, and increased risk of bone fracture. Partial agonists could …

    vt Repository record for Defining Novel Clusters of PPAR gamma Partial Agonists for Virtual Screening (opens in a new tab)

  2. Kartierung der Bindungstasche des humanen Bittergeschmacksrezeptors hTAS2R10

    Die Bittergeschmacksrezeptoren stellen in der Superfamilie der G-Protein-gekoppelten Rezeptoren eine besondere Gruppe dar. Im Menschen können die 25 Rezeptoren eine große Anzahl unterschiedlichster Bittergeschmacksstoffe detektieren. Diese Substanzen können sowohl schädlich, wie etwa Strychnin, als …

    potsdam-diss Repository record for Kartierung der Bindungstasche des humanen Bittergeschmacksrezeptors hTAS2R10 (opens in a new tab)