Global ETD Search
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Showing 1 to 1 of 1 for “"agonist radiotracer"”.
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Developing a selective sphingosine-1-phosphate-5 (s1p5) radiotracer to image oligodendrocytes using preclinical positron emission tomography (PET)
… developed from a drug development library of agonists targeting S1P5 that had shown high affinity and selectivity for their target. An agonist radiotracer would be of particular interest as S1P5 is a G-protein coupled receptor and agonists show a bias to binding receptors in the active state. …