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Showing 1 to 8 of 8 for “"aggregometry"”.
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Fibrinogen, platelet and factor XIII supplementation in cardiac surgery: In vitro and in vivo studies
… platelet function was assessed with impedance aggregometry, and clot formation with thromboelastometry. Results: Supplementation with fibrinogen improved clot formation while platelets improved both platelet aggregation and clot formation in blood samples form cardiac surgery patients (I). …
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Phenotypic Analysis of Platelets in Patients with Platelet Function Disorders
… Ratio: 97, 95% CI: 5.7-1700). Light transmission aggregometry, and DG adenosine triphosphate release (estimated by lumi-aggregometry), were not sufficiently sensitive for detecting DGD as their respective sensitivities for detecting platelet function abnormalities due to DGD were only ~52% and …
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Effects of thromboxane synthetase inhibition on blood cell function and morphology during ovine pregnancy-induced hypertension
… transmission electron microscopy and platelet aggregometry were employed to study erythrocyte morphology and thrombocyte morphology and function during ovine pregnancy-induced hypertension (OPIH). Nine multiparous gravid ewes were observed during normal pregnancy, OPIH, and thromboxane …
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Recurrent unexplained first-trimester miscarriage. Effects of acetylcalicylic acid, platelet aggregation and thyroid disease
… aggregation using multiple electrode impedance aggregometry. All women underwent the same follow-up. Primary outcome was live birth rate (LBR). In order to define reference values for the multiple electrode impedance aggregometry (the Multiplate analyzer), a longitudinal study was conducted …
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The Tetraspanin CD9 Localizes to Platelet-Platelet Contacts and Regulates Thrombus Stability
… were studied using light transmission aggregometry. CD9 perturbation increased the extent of platelet aggregation in response to threshold levels of agonist, with diminished effect with more potent agonists such as TRAP (Thrombin Receptor Agonist Peptide). CD9 perturbation also …
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Investigating small-molecule inhibitors of platelet aggregation
… ADP-induced platelet aggregation. A plate-based aggregometry assay and platelet-rich plasma (PRP) isolated from the blood of human donors were used to show that cangrelor (in nM and µM concentrations) may act in a non-competitive manner to ADP (up to mM concentrations). This is in contrast with …
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Der Einfluß von Atorvastatin auf die Serumlipide und den Aktivierungsstatus von Thrombozyten, Monozyten und Granulozyten bei Patienten mit Hyperlipoproteinämie; Typ IIa nach Frederickson
Erhöhte Serumcholesterinspiegel sind mit inflammatorischen und prothrombotischen Prozessen assoziiert, die letztlich zur Atherogenese führen. Unter einer Statintherapie konnte im Rahmen großer Interventionsstudien eine signifikante Verminderung sowohl der Morbidität, als auch der Mortalität an …
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Platelet surface receptors and melanoma metastasis
Ziel dieser Arbeit war es, die Rollen der Plättchen-Rezeptoren GPVI und GPIbα bei der hämatogenen Melanom-Metastasierung zu untersuchen. Die letzten Jahrzehnte haben zunehmend Indizien für eine Beteiligung von Plättchen und Plättchen-Rezeptoren bei der hämatogenen Tumor-Metastasierung geliefert. …