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Showing 1 to 1 of 1 for “"affinity maturation, T cell receptors"”.
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Engineering soluble, high affinity T cell receptor domains for detection of staphylococcal and streptococcal exotoxins
… stimulate a large fraction of an individual’s T cells, leading to hyperinflammation and in some cases, organ failure and death. The molecular mechanism behind hyperinflammation has been attributed to the binding of superantigen (SAg) to both a T cell receptor (TCR) on a T cell, and a class II …