Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 3235 for “"affinity"”.
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Implicit Affinity Networks
… recommendations. We propose the idea of Implicit Affinity Networks (IANs) to build, visualize, and track affinities among groups of individuals. IANs are simple, interactive graphical representations that users may navigate to uncover interesting patterns. This thesis describes a system supporting …
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Smart magnetic affinity adsorbents
… attach different polymers (thermoresponsive and affinity ligands) and their combination (thermo-affinity) at fixed positions onto M-PVA supports, either as di-block or mixed functionality polymer brushes. The configuration of introduced polymer chains as well as the haemoglobin binding …
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Advances in DNA Affinity Chromatography
<p>Different aspects of DNA affinity chromatography such as DNA complexity heparin elution, the Bi-column method and the oligonucluotide trapping method were studied. The complexity (length) of a DNA sequence attached to an affinity chromatography column affects column retention, and the purity of …
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Affinity scheduling of unbalanced workloads
… processor. The unit of work is said to have an "affinity" for the given processor, in such a case. The scheduling issue that has to be considered is the trade off between the goals of respecting processor affinities (so as to obtain improved efficiencies in execution) and of dynamically …
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Ipsative Score Distortion on Affinity 2.0
… raw scores are converted to ipsative scores on Affinity 2.0, a relatively new instrument for assessing sexual interest. Using a sample of 146 non-offending, heterosexual females, this study examined the characteristics of distorted ipsative score profiles and attempted to develop an algorithm to …
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Analysis of soluble high-affinity PD1 variants
Despite achieving significant clinical impact in several major cancer types such as melanoma or Hodgkin’s lymphoma, immunotherapies have not had much success in the treatment of pancreatic cancer. This cancer is characterised by a pro-inflammatory and immunosuppressive stroma which causes …
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Males' Ipsative Score Distortion on Affinity 2.0
… that occurs when raw score patterns of Affinity 2.0, a viewing time measure designed to assess sexual interest, are converted to ipsative scores. Eighty-eight percent of a sample of ninety-nine non-pedophilic, exclusively heterosexual males' profiles sustained some degree of distortion. …
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Affinity cryo-electron microscopy: Methods development and applications
… or short-lived. The recent development of affinity grid techniques holds great promise to tackle these challenging samples by combining the sample purification and freezing on TEM grids steps in cryo-EM grid preparation into a single step, revolutionize the grid preparation of cryo-EM, and …
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Design of a high-affinity carbohydrate binding protein
Kohlenhydrat-Protein Interaktionen sind in der Natur weitverbreitet. Sie stellen die Grundlage für viele biologische Prozesse dar, wie zum Beispiel Immunantworten, Wundheilung und Infektionsprozesse von pathogenen Viren oder Bakterien mit einem Wirt wie dem Menschen. Neben der Infektion von …
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Experiential embodiment and human immediacy: Adorno’s negative affinity
… concurs with Adorno in the thought that affinity with the object is achieved not as the resultant of identity thinking, but through the act of definite negation of identifying schema.
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Non-Pedophilic Heterosexual Male Response to Affinity 2.0
Given that the Affinity 2.0 is a largely untested instrument that purports to measure sexual attraction, it was unknown whether or not the instrument is temporally stable and would provide a characteristic response curve for normal heterosexual male sexual interest. This study examined the Affinity …
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Affinity Flow Fractionation for label-free cell sorting
… platform technology for cell separation known as Affinity Flow Fractionation (AFF) was developed. AFF relies on interaction of cells with asymmetric patterns of weak adhesive molecules allowing for continuous sorting of cells with high purity without irreversible capture of cells. Cells are sorted …
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Structure Based Drug Design of High Affinity Kras Inhibitors
… that compound 11 binds to KRAS with nanomolar affinity and completely abolishes CRaf binding in vitro, subsequently leading to a significant reduction in RAS dependent CRaf/ERK activation and son of sevenless (SOS) mediated nucleotide exchange. Moreover, treatment at low micromolar …
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Negative Surface Ionization and Electron Affinity by Mass Spectrometry
… to jon current E', the apparent electron affinity was evaluated. The values of E, the actual electron affinity were then calculated from Page's relationship: E'(0) = E + Qr - D Although this study shows that some of the ions assumed to be present in the magnetron were not observed in the …
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Engineering Soluble, High Affinity Receptor Antagonists for Bacterial Exotoxins
… the engineering of murine Vbeta8.2 for picomolar affinity to staphylococcal enterotoxin B (SEB). As the known contact regions had already been heavily mutagenized, additional engineering of the Vbeta was performed through extension of the CDR1 loop. Soluble forms of the high-affinity Vbeta regions …
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Engineering and Characterization of High-Affinity T Cell Receptors
In Chapter 6, the role of TCR affinity in T cell activation was studied using CD8-negative T cells, as well as T cells expressing the co-receptor CD8. The peptide sensitivity of T cells that expressed the highest-affinity TCRs reached a plateau, suggesting the existence of an affinity maximum for T …
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