Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 30 for “"aerosolization"”.
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Aerosolization and Atmospheric Transformation of Engineered Nanoparticles
… under controlled conditions, we developed an aerosolization technique that produces nano-scale aerosols without using solvents, which can alter the surface chemistry of the aerosols. We demonstrated the technique with carbonaceous (C₆₀) and metal oxide (TiO₂, CeO₂) nanoparticle powders. All …
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Aerosolization of Ebola Virus Surrogates in Wastewater Systems
… for the sewer model. Since information on the aerosolization of Ebola virus is quite limited, these emission rates can greatly help inform risk assessment of inhalation exposure to Ebola virus.
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Design of experimental setup for identification of parameters for optimal aerosolization of measles vaccine
… currently facing vaccine distribution. Although aerosolization is well understood, studies have focused on pharmaceuticals and very little data is available regarding vaccines. The proposed study analyzes the relationships between various pre- and post-aerosolization parameters in order to …
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Impact of a Barrier on Transport of Particles and Aerosolization of Viruses at a Wastewater Treatment Plant
… This research encompasses two studies on virus aerosolization and transport in the built environment and the subsequent implications for human health. In the first study, we quantified the impact of a barrier on the spatial distribution of different-sized particles released by speaking in a …
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Aerosolization of Drinking Water Metals to Indoor Air and Assessment of Human Taste and Visual Thresholds for Manganese
Exposure to excess manganese via drinking water raises concerns due to potential for adverse neurological impacts, particularly in children. Manganese is ubiquitous in US groundwaters above the SMCL = 0.05 mg/L. Manganese is an essential nutrient, but exposures to elevated manganese have neurotoxic …
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Getting out of the water and into the air: Understanding aerosolization of the bacterium Pseudomonas syringae from aquatic environments
… freeze water at warmer temperatures. Freshwater aerosolization processes are not well understood, particularly the role the Ice+ phenotype may play. Water samples were collected from Claytor Lake, Virginia, USA and screened for Ice+ P. syringae. Results indicated that between 6% and 15% of …
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Spray Aerosols From Saltwater to Freshwater Breaking Waves
… linked LSAs to regional cloud processes and the aerosolization of freshwater pathogens and pollutants. Yet, differences in spray aerosol ejection between freshwater and saltwater and their impact on the water-to-air dispersal of microorganisms and pollutants are poorly understood. The goals of …
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A Sensor Network for Real-Time Measurement of Aerosol Movement and Persistence for Infectious Disease Monitoring in ICUs and ORs
… ORs rapidly returned to the background after the aerosolization, with a minimum of 94 seconds and a maximum of 254 seconds due to the high air exchange rate. The ICUs had more variability. Positive pressure (door closed) and neutral pressure (door open) ICUs took the longest to clear with a …
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Purification and quantitative description of Rhodococcus equi IgG designed for aerosol nebulization to foals
… using a low volume technique prior to aerosolization (time 0) and at 0.5, 4 and 24 hours post aerosolization. The BAL fluid IgG concentration was determined and cytologic analysis was performed. The IgG concentrations of the plasma and purified IgG were 2,175 mg/dL and 1,145 mg/dL, …
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New virulence mechanisms in Yersinia pestis, the plague (Black Death)-causing bacterium: A re-emerging and bioterror pathogen
… and to investigate disease progression following aerosolization of Y. pestis in two animal models. First, we characterized Y. pestis strains lacking murein, or Braun, lipoprotein (Lpp), an outer membrane protein conserved within the Enterobacteriaceae family. We then cured wild-type and ∆lpp …
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Microbial instrumentation utilizing microfluidics
… up to 0.01% of soil bacteria can be dispersed by aerosolization and survive for more than an hour after the aerosolization process. This mechanism can be relevant for the investigation of climate change, pathogenic disease transmission, and geographic migration of bacteria. In spite of the …
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Experimental technique for optimizing aerosolized vaccine efficacy by Erika J. Sandford.
… to determine optimal parameters for vaccine aerosolization. This thesis presents an experimental setup to test Aerovax, a device designed to deliver aerosolized vaccinations in developing regions of the world. The experimental technique is the first effort to optimize vaccine aerosols across …
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Preparation and Characterization of Spray Dried Fluorescent Micro particles for Controlled Release in the Lungs.
… size showed that the particle were suitable for aerosolization into the lungs. However the dissolution study showed that showed that the powders showed an immediate release of the dyes that is within a period of 10-15 minutes and the two polymers fail to show a controlled release of the dyes that …
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Electrohydrodynamic Atomization for Improved Macromolecular Drug Delivery
… potential. For this dissertation, we explore the aerosolization of macromolecules by way of electrohydrodynamic atomization (EHDA) and how this method can be used to process and deliver therapeutics. EHDA employs a high voltage to break a column of liquid into drops. It was unknown if or how the …
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Structure-Based Drug Design Against a Biosecurity Pathogen
… survival in the environment. Infection through aerosolization triggers conversion to the metabolically active large cell variant. Disease begins in an acute phase, with flu-like symptoms and some cases develop into a chronic infection, the debilitating and potentially fatal form of Q-fever. C. …
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Characterization of Perphenazine and Scopolamine Aerosols Generated Using the Capillary Aerosol Generator
… at a series of steady state powers. At higher aerosolization powers, the low concentration formulation (9mM) degraded with dehalogenation being the major pathway. The size of perphenazine aerosols was between 0.4 to 0.6µm. Changing the solute concentration produced only small changes (~0.2µm) …
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The impact of silver nanoparticles on plant physiology
… the use of different application methods such as aerosolization.
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Effervescent proliposomes for aerosol delivery to paranasal sinuses
… potential suitability of liposomes generated for aerosolization to target paranasal sinuses. Novel effervescent proliposomes prepared with Soya phosphatidylcholine (SPC) and Dipalmitoylphosphatidylcholine (DPPC) successfully generated stable liposomes with an improved disintegration time of less …
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Adherence and Biofilm Formation of Mycobacterium avium, Mycobacterium intracellulare, and Mycobacterium abscessus in household plumbing
… of cells from biofilm and the subsequent aerosolization of microorganisms through showerheads presents a significant public health risk, particularly to those individuals with associated risk factors. Three species of NTM, Mycobacterium avium, Mycobacterium intracellulare, and …
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Development and Evaluation of a Small Volume Liquid Impaction Surface (SVLIS) in the Next Generation Impactor (NGI)
… dissolution of orally inhaled powders following aerosolization.|A custom SVLIS was designed to accommodate a liquid volume of 5 mL for incorporation in the NGI stages using the gravimetric cup. It allowed the growth of cells in a way as to mimic the thin layer of fluid lining the lung. A549 cells …
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