Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 194 for “"adverse outcomes"”.
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Unmet Health Care Needs and Adverse Outcomes for Patients with Chronic Disease
… of barriers to care and their association with adverse outcomes among patients with chronic disease. We conducted three independent studies to address this objective. Our first study provides a national perspective on the potential gaps in care for Canadians with chronic disease. Using …
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Establishment of a phenotypical model of adverse outcomes associated with assisted reproductive technologies
Beckwith-Wiedemann syndrome (BWS) is a loss-of-imprinting pediatric overgrowth syndrome. BWS is speculated to occur primarily as the result of the misregulation of imprinted genes associated with two clusters on chromosome 11p15.5, namely the KvDMR1 and H19/IGF2. There is a similar overgrowth …
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Logistical factors associated with adverse outcomes following emergency surgery in an acute care surgical unit
… The aim of this study was to describe the outcomes of emergency surgical cases, as well as determine the logistical factors associated with adverse outcomes following surgery within the unit. Methods This study was a retrospective audit which reviewed the folders of adult patients who …
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Endothelial cell plasticity as a marker of vascular disease and predictor of adverse outcomes to stress
Endothelial cells (ECs) dynamically sense and adapt to their local biomechanical and biochemical environments, a process crucial for maintaining vascular homeostasis. Loss of this plasticity is implicated in vascular diseases, where endothelial dysfunction and maladaptive responses exacerbate …
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A data-driven approach to evaluating the effectiveness and adverse outcomes of antidepressant exposure using longitudinal real-world EHR data
… explores the complex dynamics of treatment outcomes and body weight changes in patients undergoing antidepressant therapy, employing advanced machine learning techniques to model and predict clinically significant events. Depression remains one of the most pervasive and challenging mental …
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Adverse outcomes associated with timing of antenatal care initiation a retrospective cohort study of pregnancies in Cape Town, South Africa
… of antenatal care (ANC) for the prevention of adverse birth outcomes. Despite this suggestion, the population impact of early ANC remains unclear. To this end, we have undertaken a retrospective cohort study of pregnant women using public perinatal services in Cape Town, South Africa. The study …
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Structured professional judgement approach to risk assessment: generalisability across patient groups for the prediction of adverse outcomes in secure mental health care
… they can aid assessment and management of adverse outcomes beyond aggression, and 3) offering practical, empirically-derived advice for clinicians regarding management strategies that may reduce the occurrence of adverse events. This collection of papers has used considerably novel methods, …
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Prevalence, Risk Factors and Predictors of Adverse Outcomes of Febrile Neutropenia in Oncology Patients on Chemotherapy at the Red Cross War Memorial Children's Hospital: A Three Year Retrospective Study
… for home-based care in those at low risk for adverse outcomes has been identified. Aims: To evaluate the prevalence and potential risk factors for FN, identify adverse outcomes and validate a tool to identify risk for adverse outcomes in a cohort of children treated for cancer at the Red Cross …
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Signal processing approaches to analyzing patient cardiovascular state
… range corresponds to an increased risk of adverse outcomes after surgery. An analysis of blood pressures recorded during surgery could also be tied to patient fluid responsiveness, pulse pressure variability (PPV) can be a predictor of fluid responsiveness in surgical patients. Thus, a …
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Biomarkers of Cardiovascular Disease in Renal Transplant Recipients
… of cardiovascular disease are predictive of adverse outcomes in stable renal transplant recipients. <br/><br/>Patients and Methods:<br/>A cohort of 379 renal transplant recipients were studied. Prospective follow-up data (median of 16.2 years) were available for adverse outcomes including …
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A population based study of primary hyperparathyroidism in Tayside, Scotland
… data, and to investigate its long-term outcomes in the mild subgroup compared with those with severe disease. Design: A large retrospective cohort study using routinely collected data in Tayside, Scotland, 1997-2006. Results: The prevalence of PHPT is increasing annually during the study …
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Causes, management, and outcomes of polyhydramnios, at a level 2 hospital in Cape Town
… It is associated with both maternal and fetal adverse outcomes. Mild polyhydramnios is often idiopathic and pregnancy outcomes in this group are usually no worse than in the general population of pregnant women. In contrast, conditions such as congenital anomalies, chromosomal abnormalities, or …
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Predicting pulmonary hypertension and outcomes in patients with left heart disease
… form of PH worldwide and is associated with adverse outcomes. Considering the suggestions of high prevalence and potential adverse outcomes of PH in sub-Saharan Africa (SSA), the investigation of the etiologies, clinical profile, correlates, and outcomes of PH-LHD in this region is a medical …
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Towards the development of an integrated case-finding tool to facilitate the review of anticholinergic prescribing for frail older people
… (anticholinergic burden) is associated with adverse outcomes for older people. Prevalence of anticholinergic prescribing is increasing, and there is a need for tools to proactively identify at-risk patients for medication reviews. Aim: To explore the need for, and feasibility of, an …
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When working towards an optimised Carotid stenting procedure does patient, procedural and pharmacological selection impact on outcome.
… selection has the most impact on reducing adverse outcomes from the procedure. Multivariable analysis of the Sheffield database detailed in this thesis has shown that retinal events have a lower risk of adverse outcomes than cerebral events, and clopidogrel use at the time of stenting …
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Applying domain knowledge to clinical predictive models
… in predicting a patient's risk of developing adverse outcomes and in guiding patient therapy. In this thesis, we explored two different ways to apply domain knowledge to improve clinical predictive models. We first applied knowledge about the heart to engineer better frequency-domain features …
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Resilience and African American Early Adolescents: The Protective Function of Religion and Structured After-School Activities
… circumstances to achieve positive developmental outcomes. Studies of resilience and vulnerability generally reflect individuals' susceptibility to either positive or adverse outcomes when subjected to high-risk circumstances and environments. The current study examines the protective function of …
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CD68-positive tumour associated macrophages, PD-L1 expression, and EBV latent infection in a high HIV-prevalent South African cohort of Hodgkin lymphoma patients
… (TAMs) has been associated with poorer outcomes in HIV-negative patients with Hodgkin lymphoma (HL), but whether this is true in HIV positive patients with HL is not known. In this study, we investigated the number of CD68-positive TAMs and expression of programmed cell death-ligand 1 …
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The Line in the Sand: Understanding Customer Sexual Harassment Through a Psychological Contract Framework
… theory toward understanding how CSH leads to adverse outcomes, which affect individuals and organizations. A sample of 420 working women including both students and full-time non-student workers from various organizations were recruited to participate in this online study. CSH and perceptions …
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Gender Differences and the Influence of Social Support on Functional Decline in Older Persons Living With Heart Failure in Their Community
… high levels of support and positive health outcomes the objectives of this study were: 1) to determine the levels and patterns of social support, and related gender differences, 2) to determine the influence of support on functional outcomes as defined by a deterioration in physical function …
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