Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 28 for “"adverse drug reaction"”.
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A Clinical Characteristics of Adverse Drug Reaction in Pediatrics
PURPOSE: The drugs used for prevention of disease, medical treatment and research sometimes show the undesired adverse drug reactions. These unexpected adverse drug reactions are typically not related with the used capacity nor with pharmacological mechanism of individual drug. Thus, attention …
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An examination of adverse drug reaction reporting to the yellow card scheme
Chief pharmacists in 209 hospitals were surveyed about ADR reporting schemes, the priority given to ADR reporting, and attitudes towards ADR reporting. ADR reporting had a low managerial priority. Local reporting schemes were found to be operating in 37% trusts, but there were few plans to start …
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Assessing the effectiveness and challenges of adverse drug reaction reporting systems: a systematic review
Adverse Drug Reaction (ADR) reporting is a process that includes recording adverse events that are suspected to have a relationship with the utilization of medicinal products, medical devices and cosmetics. However, persistent underreporting remains a major global concern that limits the early …
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Role of pharmacists in adverse drug reaction reporting in Holy City of Makkah, Saudi Arabia. Characterisation of models for evaluating Pharmacovigilance in the Holy City of Makkah and attitude and awareness of pharmacists towards Adverse Drug Reaction Reporting.
… of the quality of life due to unexpected adverse effects. These problems may cause therapeutic failures or even drug-related morbidity and mortality. Consequently there is a need to have in place a system, conventionally known as Pharmacovigilance. The aims of Pharmacovigilance are to …
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An Expandable Stage-Based Machine Learning and Statistical Pipeline for Detecting Adverse Drug Reaction Risks on Complex Multidimensional Datasets
Adverse Drug Reactions (ADRs) are a persistent challenge to patient safety, often escaping detection in aggregate analyses. This research introduces expandable, modular pipeline that identifies statistically significant drug–ADR associations through a multivariable, propensity-adjusted framework …
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The impact of hospital surveillance programmes on the incidence of adverse drug reaction reporting in a South African teaching hospital
… that is applied to obtain information on drug experience (primarily adverse) after a drug has been approved for clinical use. One of the major problems in post-marketing surveillance studies is the lack or under-reporting of drug experiences by health care professionals. This study was …
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Application of Hyper-geometric Hypothesis-based Quantication and Markov Blanket Feature Selection Methods to Generate Signals for Adverse Drug Reaction Detection
… is the science relating to all concerns about drug safety, especially ofmanaging the risk associated with medications. It serves as a complementary approach toclinical trial. Spontaneous Reporting Systems (SRS) had been constructed world-widely tofacilitate tracking the risk of post-marketing …
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Pharmacovigilance: A comparative study about the knowledge of adverse drug reaction (ADR) reporting that private practitioners and government doctors gained in a random locality in India
<p>The present pilot study aims to compare the knowledge pertaining to ADR reporting systems that government doctors and private practitioners gained in a random, tier-II city in India, by conducting a questionnaire based survey. Their knowledge of ADR reporting, related guidelines and/or …
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Patient Centered Care Approach to Adherence with Cardiovascular Medications: Self-Determination Theory Integration
… index, along with age, insurance coverage, adverse drug reaction, adequate health literacy, illness level and number of prescription doses taken per day. Patients in the PCC group had significantly higher scores on all three SDT motivation variables, adherence index and higher portion of …
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Reducing Medication Errors by Systematically Monitoring High-Risk Medications
… timely patient laboratory monitoring and prevent adverse drug reactions (ADR) that lead to hospital readmissions. The cost of one adverse drug reaction, leading to a hospital readmission, can vary from US$2200 to US$8300, depending on the severity of the reaction. In one study, the patients who …
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A systematic approach to improving pharmacotherapy in the elderly
… would lead to a more appropriate and accurate drug use in the elderly. The elderly use many drugs and are more prone to suffer from adverse drug reaction. It is therefore important to address the quality of their drug therapy. The first study presented in this thesis showed that medication …
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The role of a pharmacist in screening, communicating and reporting the risks of cardiovascular disease associated with non-steroidal anti-inflammatory drugs and the perception of the population
… concerning non-steroidal anti-inflammatory drugs (NSAIDs), pose significant challenges to effective prevention and self-management strategies. This thesis adopts a mixed-methods approach to examine three interrelated dimensions of this issue: public knowledge of NSAID-related CVD risks, …
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Pharmacokinetics and pulmonary distribution of Draxxin® (tulathromycin) in healthy adult horses
… design and 4-week washout period were used. Drug concentrations in blood and bronchoalveolar lavage (BAL) samples were determined by ultra-performance liquid chromatography tandem mass spectrometry and pharmacokinetic parameters calculated using noncompartmental analysis. Following SC and IM …
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Development and in vivo Analysis of Inhaled Clofazimine for the Treatment of Pulmonary Tuberculosis
… infections due to its activity against TB, multidrug-resistant TB (MDR), and extensively drug-resistant TB (XDR-TB). CFZ is a highly hydrophobic with poor pharmacokinetic and adverse drug reaction profiles following oral administration. Development of an inhaled CFZ formulation could achieve high …
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Pharmacovigilance study using Electronic Medical Records
… used to detect the causal relationship between drugs and adverse drug reactions. However, SRS has limitations, such as the lack of denominator data of drug exposure, significant under-reporting problems, and time-consuming efforts and costs. In contrast to SRS data, electronic medical record …
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Investigating the genetic basis of cisplatin-induced ototoxicity in adult South African patients
… regimens, the therapeutic utility of the drug may be limited by the development of dose-limiting adverse reactions in patients. A prevalent reaction to cisplatin is ototoxicity, or drug-induced hearing loss, which occurs when the drug accumulates in and damages cells of the inner ear, …
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Immunoproteome of anti-TB drug associated DRESS in HIV TB co-infection
… A greater incidence of severe cutaneous adverse drug reaction (SCAR) such as Drug Reaction with Eosinophilia Systemic Symptoms (DRESS) occur among HIV-infected patients. We sought to characterize the immunoproteomic profile of DRESS to first-line TB drugs in HIV infected cases. We …
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A Pill for the Ill? : Depression, Medicalization and Public Health
… treatment for depression as expressed in adverse drug reaction (ADR) reports from patients, i.e. “consumers reports.” A second goal is to conduct a theoretical discussion, by looking at broad societal changes, and analyzing the consequences of mental ill health as a significant public …
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The Prevalence of Antiretroviral-Therapy-related Adverse Reactions, Hospitalisation, and Mortality among People Living with HIV in Africa-A systematic review and Meta-Analysis
… one of the major concerns remains the risk of adverse drug reactions when used by consumers. Adverse drug reactions place a burden on the healthcare system, usually as a result of complications requiring hospital admission or extended hospital admissions. In Africa, about 28.6% of adverse drug …
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