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Showing 1 to 3 of 3 for “"adventitial fibroblasts"”.

  1. Mechanism of local IL-6 production and its role in accelerating vascular inflammation leading to aortic diseases

    … There was concomitant macrophage recruitment, adventitial expansion, and development of thoracic and suprarenal aortic aneurysms and dissections in treated wild-type mice. In contrast, no dissections were produced with infusion into IL-6-/- or CCR2-/- mice over the same time period along with …

    utmb Repository record for Mechanism of local IL-6 production and its role in accelerating vascular inflammation leading to aortic diseases (opens in a new tab)

  2. Fibroblasts: Key Cells in Inflammation and Fibrosis

    … a pro-inflammatory cytokine that is secreted by fibroblasts and macrophages in the aortic adventitia and promotes the development of aortic dissections. In our previous work, analysis of aortic adventitial fibroblast secretions in vitro suggested that aortic fibroblasts were the main producers …

    utmb Repository record for Fibroblasts: Key Cells in Inflammation and Fibrosis (opens in a new tab)

  3. Hypoxia-mediated human pulmonary arterial fibroblast proliferation is dependent on p38 mitogen-activated protein kinase activity.

    … resistance vessels and thickening of the adventitial layer together with increased ECM deposition. Similar appearances are noted in the pulmonary circulation’s response to hypoxia. for this projectProlonged exposure of the pulmonary circulation to hypoxia results in vasoconstriction and …

    glasgow Repository record for Hypoxia-mediated human pulmonary arterial fibroblast proliferation is dependent on p38 mitogen-activated protein kinase activity. (opens in a new tab)