Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 15 of 15 for “"advanced microscopy."”.
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Sensorless adaptive optics in advanced microscopy techniques
… With a focus on optical trapping and nonlinear microscopy, the combination of a deformable membrane mirror and a random search optimisation algorithm is used to improve system performance at depth by pre-shaping the incoming wavefront with aberrations that are equal but opposite to those that …
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Using Advanced Microscopy Techniques for the Study of Macrophage-Cancer Cell Interactions in the Presence of Therapeutic Antibodies
The file named "VELMURUGAN-DISSERTATION-2017.pdf" is the primary dissertation file. Eight (8) supplemental files are also available and may be viewed individually.
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Phagocytosis by neutrophils - studies on phagosome dynamics and membrane traffic modulation by Streptococcus pyogenes
… magnetic bacteria to isolate phagosomes and advanced microscopy for live measurements of phagosomal pH. The employment of cell lines and their differentiation into neutrophils is shown to be a useful research tool. Using these methods, novel findings regarding mechanisms for fusion between …
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Advanced optical microscopy toolkits for non-invasive imaging in oncology
… (TPEF) and fluorescence lifetime imaging microscopy (FLIM); (2) visualizing water and lipid distribution as well as cellular morphology using coherent Raman scattering (CRS) imaging techniques in the stratum corneum, the most superficial layer of the epidermis; (3) using photoconvertible …
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Indentation induced deformation in metallic materials.
… testing, more insights can be provided with advanced microscopy techniques where the study can be focused more to understand the deformation behavior under the indenter. These experiments demonstrate that there is a wealth of information in the initial stages of indentation and has led to …
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Development of a Novel Gradient-Force Tapered Fibre Optical Tweezers System for 3D Optical Trapping at Near Horizontal Fibre Insertion Angles
… for uncomplicated integration with other advanced microscopy systems such as an atomic force microscope (AFM) for example. For use with an AFM, the optical fibre must be inserted at an angle of 10° with respect to the sample chamber floor. However, previous literature suggests that 3D …
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Quantitative Mechanical Properties of Carbon-based Surfaces Examined through Analysis of Cantilever Dynamics in Atomic Force Microscopy
… such as nanoindentation and dynamic atomic force microscopy (AFM). Although these techniques have been successful in providing a qualitative assessment of the mechanical properties of the surfaces, quantification of the experimental data has been hindered due to the lack of precisely calibrated …
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Development and application of correlative STED and AFM to investigate neuronal cells
… migration a technique combining atomic force microscopy (AFM) with stimulated emission depletion (STED) microscopy was developed. First a custom STED microscope was developed. To facilitate the design of this system the theoretical performance of a range of STED techniques (cw-STED, time-gated …
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Escherichia coli and Rhizobium leguminosarum response mechanisms to sub-lethal 2,4-dichlorophenoxyacetic acid
… I used a novel combination of methods involving advanced microscopy and metabolomics. Rlv showed an oxidative stress response, but showed adaptive capabilities with changes to specific metabolic pathways and consequent changes to its phenotype, surface ultrastructure, and physical properties …
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Imaging studies of peripheral nerve regeneration induced by porous collagen biomaterials
… the underlying mechanism. This thesis utilizes advanced microscopy to study the expression of contractile cell phenotypes during wound healing, a phenotype believed to affect significantly the final outcome. The first part develops an efficient pipeline for processing challenging spectral …
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Gallium Arsenide based photonic crystal surface emitting lasers
… are analysed, utilising transmission electron microscopy imaging of each device. It is shown how the position and size of a void in the photonic crystal region affects the threshold and slope efficiency of a PCSEL, and the results are compared to simulation, the first time a study of this kind …
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Bioinspired microvascular self-healing in polymers and composites
… the isolated construction for multiple cycles. Advanced microscopy and spectroscopy techniques are adapted for visualizing the internal microvascular networks and characterizing in situ healing agent distribution. Further development of sacrificial PLA is pursued to create more complex, branched …
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Innovative microphysiological systems for long-term real-time imaging in biomedicine
… those variables) and be compatible with the most advanced imaging methods. In the context of this industrial doctoral thesis and as a contributor of the EU-funded project ITN-DeLIVER (grant agreement n°766181), two MPS were conceived, realized, and validated at Cherry Biotech SAS. Then, the two …
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Coherence Properties Of Optical Near-fields
… experimental capabilities specific to near-field microscopy are used to investigate various aspects of the statistical properties of random electromagnetic fields in the vicinity of optically inhomogeneous media which emit or scatter radiation. The properties of such fields are being characterized …
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Elucidation of mammary gland development: combination of novel techniques to study proliferation and stem cells
… been assessed and combined with a variety of microscopy techniques to allow the multiple focal planes of the ductal network to be examined. These imaging techniques were then combined with two neutral lineage tracing models; the first, the Rosa26[CA]30 model, utilises stochastic continuous …