Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 40 for “"adrenal gland"”.
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The adrenal gland in extracorporeal circulation
<p>Due to the large volume and often conflicting results reported on postoperative endocrinological changes, the practicing surgeon has difficulty in finding applicable principles. A knowledge of these principles is however necessary for an understanding of the mechanisms responsible for survival …
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Role of serotonin in the regulation of aldosterone secretion from the rat adrenal gland
… serotonin on aldosterone secretion from the adrenal gland. To date numerous studies have reported this steroidogenic effect, describing the second messenger system utilised and in some species the receptor type involved. However the full physiological and pathophysiological role of serotonin …
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Interaction of ACTH and Estradiol in the Regulation of Growth, Differentiation, and Steroidogenic Maturation of the Baboon Fetal Adrenal Gland
… acid and/or protein levels in the baboon fetal adrenal are dependent upon fetal pituitary ACTH during mid and late gestation and the mechanism by which placental estrogen modulates ACTH actions. Administration of betamethasone (3mg/day) to baboon mothers on days 60-99 of gestation and to the …
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CARCINOMA CORTICAL DA ADRENAL NÃO FUNCIONAL COM INVASÃO DA VEIA CAVA CAUDAL EM CÃO
… and malign carcinoma are the most found between adrenal gland tumors. The present work aims to describe the case of a dog diagnosed with carcinoma in the cortex of the adrenal gland with invasion of caudal vena cava. A male dog with 15 kg, mixed breed was submitted to complementary tests, such as …
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Cloning and characterization of organic anion systems in the adrenal cortex and their role in steroid release
The adrenal steroid hormones have a central role in maintaining homeostasis, as they have influence on almost every physiological process. Their movement across the cell membrane is still poorly understood, although this is of great interest to basic biology and medicine. Previous studies have …
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Identification Of Neuroblastoma And Its Prognostic Markers Using Raman Spectroscopy
… pheochromocytoma. It is commonly situated on the adrenal gland. It displays similar histology to other small round blue cell tumors, including non-Hodgkin lymphoma, rhabdomyosarcoma, and Ewing sarcoma. One method of judging neuroblastoma aggressiveness uses tumor histology factors, including …
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Insight Into the Metabolism of Lycopene: Focus on Androgen -Dependent Tissues
… accumulate in the prostate, seminal vesicles and adrenal gland compared to the other analyzed tissues. Moreover, modulated carotenoid cleavage enzyme(s) expression in the adrenal, prostate and kidney suggested that the accumulated lyc metabolites in these tissues be involved in the observed …
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Investigation of somatomotor-sympathetic brain circuit abnormalities in two rat models featuring inborn differences in emotional behavior
… innervating sympathectomized skeletal muscle and adrenal gland, respectively, in two rat models with heritable differences in emotionality and stress reactivity: the Wistar-Kyoto (WKY) rat and the selectively bred Low Novelty Responder (bLR) rat. During our initial neuroanatomical investigations …
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Uncovering p53 Mutations and Abnormal Gene Expression in Pediatric Adrenocortical Cancer
… and mechanisms of tumorigenesis of the adrenal gland are very poorly described in the literature. However, it is well-known that the tumor suppressor p53, which is mutated in over 50% of all human cancers, is commonly mutated in pediatric adrenocortical cancer. In addition, evidence …
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A Comparison of the Neural and Hormonal Aspects of the Sympathico-Adrenal Medullary System
… dietary stresses, we have performed a unilateral adrenalectomy and denervation of the contralateral adrenal gland; throughout this work these dogs will he referred to as being adrenal denervated. After recovery these dogs were subjected to the same dietary stresses as the aforementioned animals.
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Adult behaviour and cerebral cell densities after maternal or post-weaning consumption of an obesogenic diet in mice
… HFHS diet led to increased adiposity and reduced adrenal gland mass in adult male HFHSC offspring. CHFHS mice significantly increased body mass and adiposity while adult male CHFHS mice reduced adrenal gland mass. No difference for brain mass was seen in either fetal or adult HFHSC or CHFHS mice. …
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Analyzing the Interactions Between Xenopus tropicalis MC2R, MC5R, and the MRAPs: Modeling the Regulation of Frog Interrenal Cells
<p>The role of Melanocortin 2 Receptor (MC2R) in adrenal/interrenal glucocorticoid secretion has been well documented in many organisms. Studies in mammals have shown that in the adrenal gland two melanocortin receptors and two melanocortin receptor accessory proteins are expressed: MC2R, MC5R, …
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Normal cell signals in human cancer transcriptomes
… a single-cell normal reference of the fetal adrenal gland, and explore the development of the fetal adrenal medulla, from which the childhood cancer, neuroblastoma, arises. I then compare that reference to neuroblastoma single-cell and bulk transcriptomes in chapter 3. This comparison reveals …
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The cytology of adrenocortical regeneration in the rat and the effects of x-irradiation
… regeneration after in vitro x-irradiation of the adrenal gland and (c) the response of young autotransplants to a lethal dose of whole body x-irradiation. Experimental procedures a. Immediate autotransplantation. Sixty-four male albino rats of the Wistar strain weighing between ninety and one …
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Relationship between ¹²³l-metaiodobenzylguanidine (¹²³l-MIBG) imaging findings and outcome in patients with neuroblastoma at the Red Cross War Memorial Children's Hospital
… 62% of primary tumours were located in the adrenal gland and half were NMYC amplified. Twenty (59%) patients died, 90% of deaths occurring in patients older than 12 months. No deaths were recorded in the 13 months after recruitment ended. The baseline CS did not predict outcome (alive or …
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Improving Segmentation Pipelines for Medical Imaging using Deep Learning
… the clinical workflow for diagnosing incidental adrenal masses on CT. Despite standardized reporting systems and strict guidelines for defining an adrenal mass, there exists significant inter-rater variability for this task. To enable objective and reproducible characterization of the adrenal …
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The Role of STAT and the Jak/STAT Pathway In Mediating the Effects of Interleukin-6 on StAR Expression
… a hormone produced by a hormone produced by the adrenal gland, is responsible for many regulatory functions in the body. Cortisol release is mediated by adrenocorticotrophic hormone, or ACTH, through the hypothalamus-pituitary-adrenal or HPA axis. This HPA axis is the major release pathway used …
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