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Showing 1 to 20 of 180 for “"adhesion molecule"”.
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Fatty acid regulation of adhesion molecule expression in human vascular cells.
… releases inflammatory cytokines and vasoactive molecules that produce an inflammatory reaction. The endothelium becomes increasingly permeable to LDL and an increase in adhesion molecule expression leads to leukocytes being recruited from the blood flow into the arterial wall. If the …
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Applications of Traction Force Microscopy in Measuring Adhesion Molecule Dependent Cell Contractility
… cell line to demonstrate that integrin-mediated adhesion to soft substrates causes different cell behavior than N-cahderin-mediated adhesion to soft substrates. Cells plated on laminin-coated hydrogels exhibited stiffness dependent increases in cell spreading, whereas cells plated on …
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The Regulation of Bone Marrow Mesenchymal Stem Cells by Vascular Cell Adhesion Molecule-1
… ensure hematopoietic homeostasis. Vascular Cell Adhesion Molecule-1 (VCAM1) is classically expressed on endothelial and stromal cells. While the contribution of endothelial-derived VCAM1 to BM homeostasis has been extensively studied, the specific role of MSC-derived VCAM1 remains unclear. Here …
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Mechanism of the Neural Cell Adhesion Molecule and Mode of Polysialic Acid Adhesive Inhibition
… acid on both NCAM and C-cadherin mediated adhesion. Results indicate that polysialic acid inhibits both NCAM and cadherin adhesion by increasing the intermembrane repulsion. This inhibitory effect was dependant on both polysialic acid surface density and on ionic strength.
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Role of ICAM-1, a cell adhesion molecule, in morphological changes of BV2 microglial cell
… the microglial cells. There are a series of cell adhesion molecules (CAM) related with these changes. In our present study, we studied the role of adhesion molecules including Intracellular adhesion molecule-1 (ICAM-1), which are responsible for the microglial activation using immortalized BV2 …
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Effect of IBC isolated from Psoralea corylifolia on expression of adhesion molecule-1 in cerebrovascular endothelial cells
… the effect of IBC on leukocyte-endothelial adhesion and expression of intercellular adhesion molecule-1(ICAM-1) in brain endothelial cells remains unexplored. In this study, we examined the effect of IBC on ICAM expression and leukocyte adhesion in bEnd. 3 cells and explored the possible …
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Characterizing the Nuclear Function of the Cell Adhesion Molecule Fat and Chromatin Regulation by the Inner Nuclear Membrane Protein Speg
Tissue growth, pattern formation and cell metabolism are fundamental to animal development. Coordination of these aspects requires elegant signal transduction systems. In Drosophila, fat (ft) encodes an enormous atypical cadherin that is important for such coordination. Ft functions at the cell …
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Characterization of a murine activated lymphocyte antigen (MALA-2) : the murine homologue of human intercellular adhesion molecule 1 (ICAM-1)
… displays homology with the human intercellular adhesion molecule 1 (ICAM-1), as well as human ICAM-2, human ICAM-3, and murine ICAM-2. Screening of genomic libraries yielded a partial genomic clone (4.0 kb ), containing five 3'exons and a pseudo exon. The five exons are common to both cDNAs and …
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Structure of the Chicken Neuron-Glia Cell Adhesion Molecule, Ng-CAM: Origin of the Polypeptides and Relation to the Ig Superfamily
<p>The neuron-glia cell adhesion molecule, Ng-CAM, is a cell-surface glycoprotein expressed on neurons and Schwann cells in the chicken nervous system. It is expressed as a group of related components of ~200 kD, 135 kD, and 80 kD, which are detected at particular sites during development. Ng-CAM …
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The neural cell adhesion molecule 2 (NCAM2) promotes excitatory synapse formation through increasing insulin and insulin-like growth factor 1 receptor signaling
Deletions in the gene coding for the neural cell adhesion molecule 2 (NCAM2) have been found in patients with intellectual disability. Growing evidence indicates that deficits in synaptogenesis and impaired signaling mediated by the insulin receptor and insulin-like growth factor 1 (IGF1) receptors …
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Determination of Tumor Necrosis factor-a, Interluekin-10, Interluekin-12, and Intercellular adhesion molecule-1 levels in relation to Malaria severity in children
Malaria is highly prevalent in sub-Sahara Africa and is the leading cause of morbidity and mortality accounting for approximately one million deaths per annum. Disease severity and parasitaemia have been linked to cytokine levels, but their relationship requires further elucidation. Better …
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Determination of Tumor Necrosis factor-a, Interluekin-10, Interluekin-12, and Intercellular adhesion molecule-1 levels in relation to Malaria severity in children
Malaria is highly prevalent in sub-Sahara Africa and is the leading cause of morbidity and mortality accounting for approximately one million deaths per annum. Disease severity and parasitaemia have been linked to cytokine levels, but their relationship requires further elucidation. Better …
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Probing Biological Systems at the Single Molecule Level: Studies of the Homophilic Binding of the Neural Cell Adhesion Molecule (Ncam) and Phase Dependent Lipid Anchorage Strength
… probed to determine how temperature affects the adhesion properties between adjacent lipid molecules. From this study we have shown that it takes almost three times the force to extract a lipid from a gel phase lipid layer as opposed a fluid phase layer.
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U0126, MEK1/2 inhibitor, Induces Adhesion Molecules Expression in Human Blood Cells
B₂-Integrin (CD11b) and L-selectin (CD62L) adhesion molecule play crucial roles in monocyte transmigration and adherence to endothelial cells, causing inflammatory responses in vascular lesion. MAPKinase pathway has been known to be activated in inflammatory responses. In this study, we …
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THE ROLE OF SDF-1[alpha] AS A VASCULOGENIC CHEMOKINE AND ENDOTHELIUM-ASSOCIATED CELL ADHESION MOLECULE FOR THE RECRUITMENT OF BONE MARROW-DERIVED PROGENITOR CELLS TO DEVELOPING TUMORS
… We evaluated the role of SDF-1 alpha in the adhesion of bone marrow-derived lineage-negative cells to the murine Lewis lung adenocarcinoma (LLCaB subclone), both in vitro and in vivo. LLCaB lung and liver metastases expressed significantly elevated levels of SDF-1 alpha compared to normal …
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Effects of fatty acids on inflammatory markers studies in vitro and in vivo
… inflammatory markers, including soluble adhesion molecules, in adult humans with and without CVD and to identify the effects of selected fatty acids, including eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), on inflammatory responses, especially adhesion molecule expression in …
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