Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"adenosine deaminase acting on rna"”.
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The Adar-Mavs Pathway Is A Critical Mediator of The Innate Immune System In Pancreatic Development and Cancer
<p>Adenosine deaminase acting on RNA (ADAR) is an RNA-binding protein that deaminates adenosine (A) to inosine (I). A-to-I editing is an important post-transcriptional mechanism to prevent recognition of endogenous RNA by MDA5, a cytosolic RNA sensor. Activation of MDA5 by viral RNA can stimulate …
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Reading Between the Strands: Deciphering Double Stranded RNA-Based Immune Responses in Mosquito-Virus Interactions
Mosquitoes are responsible for transmitting several medically important viruses that cause widespread illness and pose a major public health concern. Among them, Culex quinquefasciatus is a globally distributed vector species that contributes to the spread of multiple arthropod-borne viruses. …
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A-to-I RNA Editing in Human Cells
<p>RNA editing is a means of diversifying the transcriptome and regulating innate immunity. Among the different classes of enzymes that modify RNA, adenosine deaminase acting on RNA (ADAR) is a type that catalyzes adenosine-to-inosine editing on double-stranded RNA molecules to regulate cellular …
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Molecular biology of segment 8 of the influenza A virus genome
The single-stranded RNA genome of influenza A virus is divided into 8 segments, each of which encodes at least one polypeptide product. This work presents investigations into two aspects of the biology of the smallest (8th) segment: 1) a possible new gene product and 2) interactions of the viral …