Global ETD Search

Next-generation sequencing as a tool for investigating the in vivo biological consequences of DNA lesions and its applications on the ethenoguanine, 8-oxoguanine and 1,3-butadiene-induced lesions

Chang, Shiou-chi, Ph. D. Massachusetts Institute of TechnologyMassachusetts Institute of Technology2017

… and mutagenicity of four 1,3-butadiene-induced adenine adducts were evaluated. Previous in vitro studies have shown that some of these lesions are highly mutagenic. Surprisingly, we found that none of them was significantly mutagenic in any of the conditions investigated. This observation …

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Conformational analysis of DNA damaged by aristolochic acids to assess the toxicity and repair : a computational study

Kathuria, Preetleen, University of Lethbridge. Faculty of Arts and Science2015

lethbridge