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Showing 1 to 20 of 245 for “"adenine"”.
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Novel antibiotics from DNA adenine methyltransferase inhibitors
DNA adenine methylation plays a role in several core bacterial processes, including DNA mismatch repair, the timing of DNA replication and gene expression. The dependence of bacterial virulence on the activity of Dam, an adenine methyltransferase, makes it an attractive target for novel …
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Molecular tweezers: Synthetic receptors for the DNA base adenine
… and 128 were designed to complex the DNA base adenine through a combination of hydrogen bonding and $\pi$-stacking interactions. They were synthesized in a convergent fashion that was fast and efficient. A new methodology for 9-substituted acridines was developed to facilitate the syntheses of …
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The Role of Water-Adenine Complexes in Protein-Dna Interactions
"Use of these analogues will allow further studies to investigate the role of specific water-mediated interactions in protein-DNA complexes. The analogues create a ""bound"" water molecule that will be distinct from the water molecules of bulk solvent."
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The Benzoadenines: The Synthesis of Stretched-Out Analogs of Adenine
Made available in DSpace on 2014-12-10T23:02:09Z (GMT). No. of bitstreams: 1 7511588.pdf: 2816916 bytes, checksum: 7ca4dd7a092fff7c36dfb7be94619ea0 (MD5) Previous issue date: 1974
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Partial Characterization of Adenine Nucleotide Binding to Isolated Chloroplast Coupling Factor
Made available in DSpace on 2014-12-14T05:40:43Z (GMT). No. of bitstreams: 1 7726773.pdf: 4907099 bytes, checksum: 53a8598ff0c34fba7539faea61903d9c (MD5) Previous issue date: 1977
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The Synthesis and Studies of Some Adenine Nucleoside and Nucleotide Analogs
Made available in DSpace on 2014-12-10T23:00:55Z (GMT). No. of bitstreams: 1 7105227.pdf: 3677059 bytes, checksum: f0eb84f55cac8951f448deefba203a90 (MD5) Previous issue date: 1970
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Generation of Reduced Nicotinamide Adenine Dinucleotide for Nitrate Reduction in Green Leaves
Made available in DSpace on 2014-12-10T17:12:47Z (GMT). No. of bitstreams: 1 7013381.pdf: 3547242 bytes, checksum: 7069da0393d6fdbdc2ffe93673d55ccb (MD5) Previous issue date: 1969
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Identification and functional characterization of the mitochondrial adenine nucleotide carriers of Trypanosoma brucei
The Mitochondrial Carrier Family encloses a group of transmembrane proteins that transport metabolites across the mitochondrial inner membrane. The ADP/ATP carrier is the most widely studied MCF protein. It catalyzes the counter exchange of ADP for ATP in the mitochondrion of all eukaryotes. In the …
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Characterisation of the flavin adenine dinucleotide binding region in Myxococcus xanthus protoporphyrinogen oxidase
… to protoporphyrin IX, in the presence of flavin adenine dinucleotide (FAD) and oxygen. FAD is a cofactor, functioning as an intermediate electron acceptor in the catalytic function of PPOX. In this study the FAD binding region in Myxococcus xanthus PPOX was analysed by engineering and …
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From cytosine-tetraplexes to adenine-clusters : three crystal structures of DNA telomeric sequences
Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Physics, 1997.
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Influx and Efflux of Adenine Nucleotides From Erythrocytes Regulate Oxygen Transport and Systemic Metabolism
… a previously unrecognized pathway of adenine nucleotide influx and efflux that modulates erythrocyte’s oxygen binding ability and controls systemic metabolism. Our studies show that the loss of AMPD3 and CD73, two important enzymes in regulating AMP levels intra- and extra-cellularly, …
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Inhibitation of succinate oxidation in beef heart mitochrondria by derivatives of pyridine adenine dinucleotide
This document only includes an excerpt of the corresponding thesis or dissertation. To request a digital scan of the full text, please contact the Ruth Lilly Medical Library's Interlibrary Loan Department (rlmlill@iu.edu).
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Novel derivatives of nicotinamide adenine dinucleotide (NAD) and their biological evaluation against NAD-consuming enzymes
Nicotinamide adenine dinucleotide (β-NAD+) is a primary metabolite involved in fundamental biological processes. Its molecular structure with characteristic functional groups, such as the quaternary nitrogen of the nicotinamide ring, and the two high-energy pyrophosphate and nicotinamide …
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Solubilization, Reconstitution and Fractionation of the Membrane Reduced Nicotinamide Adenine Dinucleotide Oxidase of Bacillus Megaterium Km
Made available in DSpace on 2014-12-12T00:36:21Z (GMT). No. of bitstreams: 1 7105287.pdf: 4329453 bytes, checksum: 23c37bf533d20ad31c5e20aa167bc7e0 (MD5) Previous issue date: 1970
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Role of carbohydrate in control of the adenine nucleotide pool in human skeletal muscle during exercise
… between carbohydrate (CHO) availability and the adenine nucleotide pool in human skeletal muscle during exercise has been investigated during short-term high intensity cycling exercise (Study I), or sustainable heavy cycling exercise (Study II), with and without prior muscle glycogen lowering. In …
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DNA and Ligand Binding and Kinetic Properties of Wild-Type and Mutant RsrI [n6-Adenine] DNA Methyltransferases
To complement the biochemical characterization of M•Rsr I in vitro, DNA binding analysis in vivo was performed using the bacteriophage P22-based challenge-phage assay. I isolated a catalytically impaired mutant, M•RsrI (L72P), that, unlike wild-type M•RsrI, binds in a …
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