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Showing 1 to 10 of 10 for “"adaptive radiation therapy"”.
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Adaptive Radiation Therapy Of Prostate Cancer
… actual dose delivered to the patient. Then the adaptive plans were compared to the original plan to evaluate tumor control and normal tissue complication using radiobiological model. Different PTV margins were also studied to access margin reduction techniques. If the actual dose delivered to …
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Improving Cone-Beam Computed Tomography Based Adaptive Radiation Therapy with Deep Learning
During radiation therapy, patient anatomical changes may compromise treatment quality if the treatment plan, prepared prior to therapy, remains unchanged throughout the course. Adaptive radiation therapy (ART) has been developed to address this issue by adapting the treatment plan based on …
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Development of Advanced Mr-Guided Adaptive Radiation Therapy Methods For Head & Neck Cancers On The 1.5T Mr-Linac
… neck cancers (HNC). This device enables on-line adaptive radiation therapy (ART) based on anatomical changes throughout treatment and variations in patient position. This novel technology also has the potential for advanced ART strategies such as dose-optimized ART, in which the treatment plan is …
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Optimizing Kilovoltage Cone-Beam Computed Tomography for Image-Guided Radiation Therapy
… CBCT) has important applications in image guided radiation therapy (IGRT). In its current state, CBCT is suboptimal for these applications due to its considerable radiation dose, poor soft-tissue contrast and inaccurate Hounsfield Units as a result of in-patient scatter. The specific aims of this …
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Direct optimization of 3D dose distributions using collimator rotation
… is to improve the precision and efficiency of radiation therapy treatment. This goal is achieved by developing and implementing a direct aperture optimization (DAO) platform where the multileaf collimator (MLC) is rotated between each aperture. The approach is referred to as rotating aperture …
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Optimization of Image Guided Radiation Therapy for Lung Cancer Using Limited-angle Projections
… developments of highly conformal and precise radiation therapy techniques promote the necessity of more accurate treatment target localization and tracking. On-board imaging techniques, especially the x-ray based techniques, have found a great popularity nowadays for on-board target …
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Ai-Enabled Online Plan Adaptation For Mr-Guided Stereotactic Ablative Radiotherapy (Sabr) of Head and Neck Cancer
… type worldwide. Stereotactic ablative radiotherapy (SABR) has emerged as an effective treatment for HNC, delivering highly conformal doses to the tumor target while sparing surrounding normal tissues with a sharp dose gradient. However, the accuracy of the treatment delivery is limited by …
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Adaptive Intensity Modulated Radiation Therapy Planning Optimization with Changing Tumor Geometry and Biology Enforcing Both Cumulative and Fraction Size Dose Constraints
<p>Intensity Modulated Radiation Therapy (IMRT) is a modern technique of delivering radiation treatments to cancer patients. In IMRT technology, intensities must be chosen for the many small unit grids into which the beams are divided to produce a desired distribution of dose at points throughout …
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Forecasting Longitudinal Changes In Oropharyngeal Tumor Volume, Position, and Morphology During Image-Guided Radiation Therapy
… tumor volume, position, and morphology during radiation therapy.</p> <p>One volume, one position, and two morphology (size, shape, and position) feature vectors were used to describe 35 oropharyngeal gross tumor volumes (GTVs) during radiation therapy. The two morphology feature vectors …
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Image-Guided Proton Therapy For Online Dose-Evaluation and Adaptive Planning
<p>The main advantage for using protons in radiotherapy is their finite range in patients, allowing for potential improved sparing of normal tissues. However, this comes at a cost of increased sensitivity to range uncertainties. Density changes along the beam path will affect the proton range and …