Global ETD Search
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Showing 1 to 5 of 5 for “"acyl radical"”.
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An Acyl Radical Cascade Model for the Total Synthesis of Lyconadin A
… to 1 based on a novel 7-exo-trig/6-exo-trig acyl radical cascade cyclization. The synthesis of model acyl radical cascade precursor 23 will be presented. Key features of this synthesis include the suppression of competing elimination during the alkylation of a hindered phenethyl bromide and …
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Model Studies Towards the Total Synthesis of Lyconadin A via An Acyl Radical Cascade Reaction
… synthesis of Lyconadin A was proposed via an acyl radical cascade reaction. To investigate the possibility and stereoselectivity of the cascade cyclization, phenyl selenoester 16 was chosen as a model substrate to study the 7-exo-5-exo radical cyclization. A synthetic route to phenyl …
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Chiral acyl radicals generated by visible light enable stereoselective access to 3,3-disubstituted oxindoles: application toward the synthesis of (–)- and (+)-physovenine
Radical species serve as powerful tools for carbon-carbon bond formation in synthetic organic chemistry. Such species can be formed in an efficient and environmentally friendly manner by way of photoredox catalysis, which uses a photocatalyst in conjunction with visible light (typically) to …
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Studies towards the syntheses of the citreamicins
… reaction was accomplished. Finally, a novel acyl radical cyclization was employed to construct the pentacyclic core of citreamicin η under mild reaction conditions.
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Development of New Organic Photoredox Catalysis Driven by Visible Light
… atom transfer (HAT) to selectively generate acyl radicals from corresponding aldehydes without inducing crossover reactivity of thioesters. In situ formed acyl radicals then react with thiosulfonate S-esters to efficiently produce thioesters. The mild and efficient method exhibits excellent …