Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 29 for “"acute phase protein"”.
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Serum Lipocalin-2 (LCN-2) as a major acute phase protein under different pathological conditions in vivo and in vitro studies
… ist eine pleiotrope 25-kDa sekretorischen Proteins, das derzeit als Biomarker für Nierenschäden und Entzündungen eingesetzt. Sein Serumspiegel unter verschiedenen pathologischen Bedingungen erhöht, aber die Quelle und Ursache sind unklar. Das Ziel unserer Studie war es, zur prospektiven …
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The effect of a dietary phase 2 protein inducer on inflammatory parameters in blood and liver of spontaneously hypertensive stroke prone rats
… of oxidative stress is the inflammatory acute phase protein response. Oxidative stress and its accompanied inflammation can be reduced via phase 2 enzyme induction. Broccoli sprouts, a rich source of phase 2 enzyme inducers such as isothiocyanates, can be incorporated into the diet to …
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Physiological and Biochemical Aspects of Methionine Isomers and Precursors in Broilers
… activity, blood antioxidant profile (e.g., acute phase protein, leukocyte count), intestinal nutrient transporter gene expression, Met converting enzyme gene expression and activity, oxidative stress markers, and a potential pathway related to amino acid signaling. To achieve this goal, male …
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Equine Septic Arthritis and Serum Amyloid A
… characterized by significant elevations in total protein (TP) and total nucleated cell count (TNCC). However, in some cases it can be difficult to distinguish between septic arthritis and non-septic joint inflammation (synovitis) based on clinical signs and synovial fluid cytology alone. A rapid …
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Characterising the role of haptoglobin in experimental subarachnoid haemorrhage.
… The role of haptoglobin (Hp), a systemic acute phase protein and the primary Hb-scavenging molecule, has recently been postulated to play a role in the pathogenesis of cerebral arterial vasospasm and delayed neurological deterioration in patients suffering SAH. The aim of this project was …
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SERUM AMYLOID A IN RUMINANTS: DIAGNOSTIC VALUE AND FOOD CONTAMINATION ASSESSMENT
… in this thesis were to investigate the bovine acute phase protein Serum Amyloid A, focussing on its value as safety marker in farm animals. SAA can be considered as a natural anti-inflammatory and immunomodulatory agent and local expression of SAA, at the site of the initial acute phase …
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Plasmatische und zelluläre, nicht invasive Biomarker für die Diagnostik kardialer Abstoßungsreaktionen
… markers of cardiac rejection. The search for protein markers in cardioplegia solutions revealed that increased activation of the complement system may occur in the context of primary graft failure. This assumption is supported by an increased presence of the acute-phase protein CRP. Platelets …
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The effects of E-cigarettes on pulmonary inflammation and inflammasome activation
… profile as measured by inflammatory cytokine and acute phase protein content. These data highlight that vaporisation of E-liquid produces vapours that are not benign to human cells and can cause inflammatory dysregulation.
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Mechanism of Transcriptional Regulation of C-Reactive Protein Gene Expression.
<p>C-reactive protein (CRP) is an acute phase protein produced by hepatocytes whose serum concentration increases in inflammatory conditions including cardiovascular complications. Statins that are used in the treatment of cardiovascular diseases to reduce cholesterol also lower serum CRP levels. …
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Analytical validation and evaluation of the effects of intramuscular injections on acute phase proteins in horses
Acute phase protein (APP) measurement can be used to characterize and detect inflammation, as well as monitor response to therapy. Intramuscular (IM) injections often result in local swelling and inflammation, which may lead to increased plasma concentrations of APP. The first objective of this …
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The plasma protein fetuin: common structural features of the mammalian fetuin family
… expression of the bovine plasma glycoprotein fetuin and its homologues in other species has been examined. From the known partial amino acid sequence of bovine fetuin, degenerate oligonucleotide probes were designed. These probes were end-labelled using 14 polynucleotide kinase and …
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IDENTIFICAZIONE DI NUOVI BIOMARKER E METODI ANALITICI INNOVATIVI IN PATOLOGIA CLINICA VETERINARIA
… a probable biological behaviour as a negative acute phase protein. 3. Hypertension markers: homocysteine and entothelin-1 (ET-1). Hypertension usually is secondary to diseases that indirectly could affect the systemic pressure, mainly renal and heart diseases. Homocysteine appears increased in …
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STAT3-protein interactions in IL-6/gp130 signaling
… examined by using gamma-Fibrinogen (ã-FBG), an acute phase protein, as a model. IL-6 induces a strong nuclear association of STAT3 with CDK9, which is mediated via both STAT’s NH2-terminal and COOH-terminal domains. The induction of ã-FBG by IL-6 is significantly decreased when CDK9 is repressed …
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Cloning, Expression and Purification of the Different Human Haptoglobin Chains and Initial Characterization by Mass Spectrometry
Haptoglobin (Hp) is an acute phase glycoprotein that exists in all vertebrates and can be found in the majority of body fluids. It is phenotypically variant in humans and presents in two allelic forms: Hp1 and Hp2. The two forms vary by the identity of their light chains: L1 or L2 for Hp1 and Hp2, …
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A neutral protease of the neutrophil surface : role in the proteolysis of C-reactive protein and fibrinogen
Both of the acute phase reactants, C-reactive protein and fibrinogen, as well as neutrophils have been shown to accumulate at sites of tissue injury or inflammation. The association of C-reactive protein with neutrophils and the concomitant degradation of this ligand by a phorbol 12-myristate 13 …
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Characterization of Pleiotropic Activities of alpha1-Antitrypsin
… inflammatory cells. alpha1-antitrypsin (AAT), an acute phase protein, is the prototypic member of the serpin super family and a major inhibitor of serine proteases such as neutrophil elastase. The clinical importance of AAT is highlighted in individuals with inherited AAT deficiency who exhibits …
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The role of Serum Amyloid A1(SAA1) in coronary artery disease
… (SAA1) and serum amyloid A2 (SAA2) (A-SAA) are acute-phase proteins (APPs); the concentration of A-SAA can increase by 500-1000 fold during an acute systemic inflammation (Malle et al. 1993). The predominant form of A-SAA in plasma is reported to be SAA1 (Yamada et al. 1999). A-SAA has …
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Transcriptional adaptation of adipose tissue in dairy cows in response to energy overfeeding
… of pro-inflammatory cytokines, chemokines, and acute-phase protein. In conclusion, overfeeding energy may increase visceral AT secretion of pro-inflammatory cytokines by stimulating fat accumulation in visceral AT depots. (For the contents in chapter 3 and 4) In experiment 2, mRNA samples of MES …
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Clinical utility of serum amyloid A to differentiate feline disease processes using a newly validated point of care assay
DSpace SAF Submission Ingestion Package generated from Vireo submission #17965 on 2022-11-14 at 17:34:07
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OMICS APPROACHES FOR OMEGA-6/OMEGA-3 POLYUNSATURATED FATTY ACID RATIO IN PIGS
… linked to lipolysis, obesity, myogenesis, and protein catabolism. We also determined on how sow diets with high or low n-6/n-3 PUFA ratios of 13:1 (SOY) and 4:1 (LIN), influenced the reproductive performance of sows, growth performance of pre-weaned piglets, and fat deposition, including …
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