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Showing 1 to 14 of 14 for “"acute lung injury,ALI"”.
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Der Sauerstoffverbrauch der Lunge (VO2pulm) bei Patienten mit Acute Lung Injury (ALI) und Acute Respiratory Distress Syndrome (ARDS) unter mechanischer Beatmung und PEEP-Variation, gemessen als VO2-Differenz zwischen indirekter Kalorimetrie und Berechnung über das inverse Fick´ sche Prinzip
Bei Patienten mit einem akuten Lungenversagen (ALI oder ARDS) ist der Sauerstoffverbrauch der Lunge (VO2pulm) durch pathophysiologische Prozesse insbesondere die Ausbildung von Atelektasen stark beeinträchtigt. Aufgrund der Annahme, dass eine Steigerung der Anzahl ventilierter Lungenareale zu einer …
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Die Beatmung mit niedrigen Tidal-Volumina verbessert die zerebrale Gewebeoxygenierung im experimentellen Tiermodell des akuten Lungenversagens
… in fourteen female pigs with experimental acute lung injury (ALI) induced by surfactant depletion: 1) low tidal volume ventilation (LT) with 6 ml/kg body weight, 2) high tidal volume ventilation (HT) with 12 ml/kg body weight. For each condition, gas exchange, haemodynamics and continuous …
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Effekte von Iloprost auf Hämodynamik und Gasaustausch beim akuten Lungenversagen : eine tierexperimentelle Studie
ARDS (acute respiratory distress syndrome) is characterized by an intrapulmonary mismatch between ventilation and perfusion, resulting in grave hypoxemia, pulmonary hypertension, high pulmonary right-to-left shunt and complex inflammatory events. In spite of modern proposals of therapy, it leads to …
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Staphylococcal Enterotoxin B-Induced Acute Lung Injury:Mechanism and Treatment of Disease
<p>Acute lung injury (ALI) remains as an important health condition in intensive care units all over the world, with approximately 200,000 cases per year in the United States only. ALI can develop as a medical complication following inhalation of a toxic substance, septic shock, blood transfusions …
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Prostacyclin-Inhalation in Kombination mit Almitrine zur Therapie des akuten Lungenversagens
… on pulmonary ventilation-perfusion ratio in acute lung injury (ALI) compared to inhaled prostacycline or intravenous ALM alone. Experimental ALI was established in all 24 pigs (weighing 30+/-3 kg) by repeated lung lavage. Animals were randomly assigned to receive either 25 ng/kg/min inhaled …
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Incidence and Pathogenesis of Acute Lung Injury and the Acute Respiratory Distress Syndrome in Humans
Acute lung injury (ALI) and it’s more severe form, acute respiratory distress syndrome (ARDS), are conditions characterised by neutrophilic pulmonary inflammation, refractory hypoxaemia and diffuse alveolar damage. This work reports on the first UK based prospective study of the incidence and …
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Extrakorporale Membranoxygenierung mit dem DeltaStream-System bei experimentell induziertem akutem Lungenversagen
Acute Respiratory Distress Syndrome (ARDS) and Acute Lung Injury (ALI) belong to the most frequent indications for admission to an intensive care unit. Both ARDS and ALI are mainly characterized by a ventilation-perfusion mismatch resulting in intrapulmonary shunting and hence in hypoxemia and …
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Identification of Host and Parasite Factors Mediating the Pathogenesis of Severe and Cerebral Malaria
… each tissue examined (brain, liver, spleen and lung), showed differential gene expression between CM-resistant and susceptible hosts, and were most prominent in lung tissue. Closer examination of lung involvement in PbA infection revealed that PbA-infected C57BL/6 mice develop acute lung injury …
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Mechanisms of imporvement following functional inhibition of nitrosative stress after brun and smoke-induced acute lung injury
… flame burn and smoke (B + S) inhalation induces acute lung injury (ALI) and results in the loss of pulmonary function. A cascade of molecular and cellular events initiates the formation of reactive oxygen/nitrogen species (ROS/RNS) that in turn drives an inflammatory response and consequently …
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Influenza A Virus PB1-F2 Protein: its Role in Pathogenesis
… pandemics resulting in significant levels of mortality and socio-economic costs worldwide. PB1-F2 is a small non-structural protein encoded by an alternate +1 open reading frame in the PB1 gene. PB1-F2 is considered to play important roles in primary influenza virus infection and post-influenza …
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PERFLUOROCHEMICAL AUGMENTED INTRATRACHEAL DELIVERY OF ANTIOXIDANT ENZYMES AND GENES TO ATTENUATE OXIDATIVE STRESS-INDUCED LUNG AND RESPIRATORY MUSCLE ALTERATIONS
… loading of the respiratory muscle. These abnormalities of pulmonary structure and function increase the work of breathing necessitating increased respiratory muscle force production to maintain alveolar ventilation. When the load placed on the respiratory muscle pump exceeds its capacity, …
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Role of Soluble [alpha]-Klotho in the Alleviation of Acute Lung Injury
… our modern environment. These insults can cause acute lung injury (ALI), a syndrome characterized by inflammation, increased permeability, and pulmonary infiltrates. Moderate ALI causes hypoxemia, leading to respiratory failure if left unattended. Patients with severe ALI develop acute …
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Acute pancreatitis, from local defense to remote organ injury
Acute pancreatitis (AP) is an inflammatory disease of the pancreas. Acute abdominal pain is the most common symptom. Pancreatic injury is mild in 80% of patients, who recover without complications. The remaining patients have a severe disease with local and systemic complications such as acute lung …
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Targeted Delivery of Surface Modified Nanoparticles: Modulation of Inflammation for Acute Lung Injury
… of pulmonary inflammation associated with acute lung injury (ALI) using novel surface modified nanoparticles. ALI is characterized by three main pathological events: I) pulmonary edema, II) excessive pro-inflammatory cytokines and chemokines production from alveolar epithelial and …