Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 99 for “"actinobacteria"”.
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Screening of actinobacteria for novel antimalarial compounds
… Filamentous members of the bacterial phylum, Actinobacteria, are well-known antibiotic producers, but their antimalarial potential has not been well investigated. This makes these actinobacteria a potentially valuable source of novel antimalarial compounds. To evaluate the antimalarial …
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Oxidative Protein Folding Pathways In Gram-Positive Actinobacteria
… <p>This thesis reveals that Gram-positive Actinobacteria use disulfide bond formation to help fold secreted proteins in the exoplasm. Using the assembly of adhesive pili as a marker for disulfide bond formation in <em>A. oris</em> and <em>C. diphtheriae</em>, we found that protein oxidation …
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Screening rare filamentous actinobacteria for novel antimycobacterial compounds
… Both these bacteria belong to the phylum Actinobacteria. Due to this history, filamentous actinobacteria were selected for screening of novel antimycobacterial compounds. However, the focus in this investigation was on species from understudied genera, the so-called “rare actinobacteria” …
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Screening of South African marine filamentous actinobacteria for antitubercular compounds
… to treat TB more effectively. The filamentous actinobacteria are a viable source of potential novel antitubercular drugs especially with the advent of technological advancements providing the means to overcome the issues that hampered natural product drug discovery in the past. For example, …
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Isolation, identification and characterisation of novel actinobacteria from Zambian hot-springs
… was to isolate, characterise and screen novel actinobacteria for industrially relevant enzymes including hydantoinases. Fifty one actinobacteria were isolated. Isolates were characterized by a polyphasic approach using standard methods, combining phylogenetic analysis of the 16S rRNA gene, …
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Isolation and characterisation of indigenous actinobacteria from diverse South African environments
… plant and seaweed samples were used to isolate actinobacteria, with a particular focus on isolating rarer actinobacteria (non-Streptomyces species). A total of 169 putative actinobacterial strains was isolated, of which 42 were selected, based on their morphology, for further identification …
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Screening environmental actinobacteria for antimycobacterial antibiotics and characterisation of Kribbella stellenboschensis sp. nov
… GOT) 135 isolates were putatively identified as actinobacteria based on colony morphology. These isolates were screened for antimycobacterial activity against the test bacterium Mycobacterium aurum A+. A Kribbella strain, isolated and identified by an intern in the lab, and a Micromonospora …
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Insights Into The Reactivation, Regulation and Essentiality of Oxidative Protein Folding Pathways In Actinobacteria
… and pathogenicity. In the Gram-positive actinobacterial pathogens <em>Actinomyces oris </em>and <em>Corynebacterium diphtheriae</em> oxidative protein folding is catalyzed by the primary thiol-disulfide oxidoreductase MdbA. MdbA is required for assembly of adhesive pilus, which mediate …
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An investigation into the enzymatic activity of deepsea actinobacteria in decolourising crystal violet dye
Crystal Violet (CV) decolourising deep-sea actinobacteria could provide a great source of novel redox biocatalysts that can be used in various applications such as removal of triphenylmethane dyes from contaminated wastewater and soil, degradation of aromatic environmental pollutants, …
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Screening for novel compounds produced by Actinobacteria and Gardnerella vaginalis that impact HIV-1 infection
… whether NPs produced by selected filamentous actinobacteria and the BV-associated bacterium (BVAB) Gardnerella vaginalis (GV) could impact HIV infection. NPs from 23 actinobacteria strains were extracted and tested on pseudovirus (PSV) infection. Ten strains showed a range of anti-viral …
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Diversität und Dynamik von Bakteriengemeinschaften in vier ausgewählten Seen der Mecklenburgischen Seenplatte
… Bakterienfraktionen. In allen Seen wurden die Actinobacteria als eine der dominanten Bakteriengruppen identifiziert. Innerhalb der Actinobacteria konnten neue Cluster und Subcluster beschrieben werden. Sowohl die gesamten Bakteriengemeinschaften wie auch die Actinobacteria zeigten ausgeprägte …
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The application of actinobacterial extracts for plant growth promotion
… stress conditions. In this study, 27 actinobacterial strains isolated from South African medicinal plants Aloe ferox and Sutherlandia frutescens, were evaluated for their potential as candidate bioinoculants under normal and stressed (drought and salinity) conditions. Phenotypic …
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Comparison of Subterranean Termite (Rhinotermitidae: Reticulitermes) Gut Bacterial Diversity Within and Between Colonies and to Other Termite Species Using Molecular Techniques (ARDRA and 16S rRNA Gene Sequencing)
… Spirochaetes, Bacteroidetes, Firmicutes, Actinobacteria, and the newly proposed "Endomicrobia," were discovered. Further analysis indicated that the gut of R. flavipes may harbor as many as 1,318 ribotypes per termite. The second objective was to determine if the gut bacterial diversity …
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Diversity and distribution of Tylosema esculentum (Marama bean) endophytic bacteria communities in Omitara, Harnas and Otjinene, eastern Namibia
… (67.4%) followed by Firmicutes (23.7%) and Actinobacteria (4.3%). Shannon diversity index, revealed a significant difference between the tuberous roots and leaves (p = 0.005) and stems (p = 0.006) microbial communities. The cluster analysis revealed a separation between the above and below …
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Bakterieller Abbau von refraktärem organischem Material im Weserästuar und in der Nordsee
… zeigten eine Dominanz der Gammproteobacteria und Actinobacteria. Die Veränderung der Salzgehalte in den Inkubationsmedien, im Vergleich zum Salzgehalt des Habitats, aus welchem die Bakteriengemeinschaften stammten, führte zu einem verstärkten Abbau der Huminsäuren. Obwohl zuerst ausschließlich die …
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Bacterioplankton in the Chesapeake Bay: Genetic diversity, population dynamics and community proteomics
… Cyanobacteria and Actinobacteria were the dominant groups while in the winter, Alpha- and Betaproteobacteria, and Actinobacteria were commonly found. Clone library analysis also revealed dramatic shifts in bacterial species composition between seasons. Unique SAR11, …
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Biosynthetic and Functional Studies of Bacillithiol in Gram-positive Bacteria
… and mycothiol (MSH) as the dominant LMW thiol in Actinobacteria. Functional studies on those thiols have revealed their importance in cell metabolism, also their potential as target for antimicrobial development. Interestingly, neither GSH nor MSH was found in low G+C Gram-positive bacteria, …
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Detection and Capture of Nitrogen Fixing Bacteria From Soil and Roots Using Plant Specific Lectins
… diazotrophs and other nutrient cyclers such as: Actinobacteria, Alphaproteobacteria, Bacilli, Betaproteobacteria, Chloroflexia, Cytophagia, Deltaproteobacteria, Gammapoteobacteria, and Sphingobacteriia.</p>
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Sources of Variation in the Microbiome of Pre-Weaned Dairy Calves
… Bacteroidetes, Firmicutes, Proteobacteria, Actinobacteria, Cyanobacteria, Verrucomicrobia, Spirochaetes, Tenericutes, Fibrobacteres, and Lentisphaerae. Overall, the calf meconium and fecal microbiome is influenced by a combination of the maternal vagina, oral, and fecal microbiomes. Further …
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