Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"actin depolymerizing factor"”.
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The Role of Actin Depolymerizing Factor in Regulating Actin Dynamics in Toxoplasma gondii
… Gliding and invasion are dependent on parasite actin filaments, yet parasite actin is mostly non-filamentous. Filaments have been detected only transiently during gliding, suggesting that parasite actin filaments are rapidly assembled and disassembled during gliding motility. Little is known …
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Isolation and sequencing of a genomic clone of ESI28 : an early salt-stress induced gene of the salt-tolerant wild wheatgrass Lophopyrum elongatum
A genomic sequence corresponding to a putative actin-depolymerizing factor (ADF) was isolated from a wheat (Lophopyrum elongatum) genomic library. The genomic clone, designated ESI28-G-5, codes for the ESI28 gene (early salt-stress induced). The 5$\sp\prime$-upstream sequence contains a putative …
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Regulation of Cell Migration by WNK1
… stimuli, including growth and chemotactic factors, hormones, and elements of the extracellular matrix. My graduate research has focused on the regulation of cell motility by a serine/threonine protein kinase, WNK1 (With No lysine (K)1), so named because of the absence of a conserved lysine …
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Pathological Upregulation of a Calcium-Stimulated Phosphatase, Calcineurin, in Two Models of Neuronal Injury
… dephosphorylation and activation of cofilin, an actin-depolymerizing factor. Calcineurin-activated cofilin induced an increase in actin depolymerization, a mechanism shown to cause spine loss in other models. Finally, via Golgi impregnation, we demonstrated that status epilepticus-induced spine …
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Simulated impact trauma and osteoarthritis: the role of cell volume and mechanotransduction
… showed that hypertonicity increased cortical actin by 29 % within the superficial zone (SZ) only (p<0.01). Volume and actin polymerisation regulation are governed by intracellular Ca2+ and the regulatory volume decrease (RVD) inhibitor REV5901 has been linked to both and was therefore tested …