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Showing 1 to 4 of 4 for “"acridone"”.
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Investigation of Dual Stage Acridones as a Potent Malaria Treatment
… falciparum</em> is urgent. Discovery of novel acridone chemotypes have shown promise for a new antimalarial drug treatment. Presently, two acridone chemotypes have intrinsic antimalarial potency against chloroquine sensitive and multidrug resistant parasites. Acridones lacking an N10 side chain …
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Reactions of some non-enolisable chloroketones with amide ion and a new synthesis of acridones /|nGuo-shyoung John Chen. -- 260 St. Catharines, Ont. : [s. n.],
… the 2'- and 3' -ch.loroketones gave N-benzoylacridone on treatment with potassium amide in ammonia; an aryne mechanism is involved for the 3'-chloroketone but aryne and nucleophilic substitution mechanisms are possible for the 2'-chloroketone. Hydrolysis of the 2'- and 3'-chloroketones gave …
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Towards Self-assembling Multichromophoric Materials for Organic Semiconductors
… change upon excitation. Second, analogous acridone derivatives were synthesized and investigated to explore the differences in optical properties. They did not exhibit a large geometry change upon excitation but underwent intramolecular charge transfer, enhancing the absorption properties …
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Design, Synthesis and Study of Novel Nucleobase Analogs
… solution, thus liberating the highly fluorescent acridone moiety. Moreover, three novel fluorescent 7-deaza-2´-deoxyadenosine analogs were successfully synthesized via the Sonogashira cross-coupling reaction of 7-iodo-7-deaza-2´-deoxyadenosine with 1-ethynylpyrene, 2-ethynyl-6-methoxynaphthalene, …