Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 22 for “"acoustic startle"”.
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Acoustic Startle Response in High and Low Hostiles Before And After A Cold Pressor Task
… regulatory control would also be evident in the Acoustic Startle Response (ASR). In this experiment, high- and low-hostile undergraduate men (N = 40) were exposed to a series of startle probes before and after a cold pressor (CP). Startle responses were measured using electromyography (EMG) …
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AN EXAMINATION OF CHANGES IN THE SOUND ENVIRONMENT AS MODULATORS OF THE HUMAN ACOUSTIC STARTLE RESPONSE IN CONTROL AND TINNITUS SAMPLES
… goal of this project was to determine whether a startle reflex paradigm could be used as a detector of tinnitus symptoms. The startle response is a brainstem reflex, initiated by sudden change in the environment. Responses can be facilitated by embedding a startle stimulus in background noise, or …
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Effects of Exposure to Perinatal Ultrasound Radiation on Information Processing in the Auditory System
… task to test for appropriate motor responses. Acoustic startle and prepulse inhibition tests were administered to test for sensorimotor gating, hearing, and motor response. Finally, a brainstem auditory evoke potential test was given to track auditory threshold and appropriate neural firing at …
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Cognitive dysfunction studied in animal models of schizophrenia
… the prepulse inhibition and habituation of the acoustic startle response models respectively. Additionally, selective attention was investigated using latent inhibition in taste aversion conditioning. Systemic administration of PCP to mice caused a deficit in habituation of the acoustic startle …
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Prenatal stress alters fear-conditioned behaviors and the response to serotonergic drugs
… prenatally stressed (PS) rats, most notably the acoustic startle response and behavioral inhibition (i.e. freezing). PS rats do not differ in baseline peak startle responding, or in the habituation of the peak startle response when compared to the non-prenatally stressed (CON) rats. However, PS …
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Prepulse inhibition come strumento diagnostico per lo studio del comportamento impulsivo-aggressivo nella schizofrenia
… through the prepulse inhibition (PPI) of the acoustic startle reflex. Notably, PPI deficits are associated with numerous neuropsychiatric conditions characterized by gating disturbances and personality aggressive traits, including schizophrenia and Tourette syndrome. Nevertheless, the …
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ANXIETY AND INITIAL VALUE DEPENDENCY IN STARTLE HABITUATION
… (CA) relate to habituation kinetics of the startle eyeblink response—initial value, linear slope, and the relationship between them (initial value dependency, or IVD). In study 1, participants (n=31; 15 control, 16 CA) were exposed to two blocks of acoustic startle stimuli, and CA …
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The impact of serotonergic and dopaminergic genetic variation on endophenotypes of emotional processing
… this end, two well established paradigms – the acoustic startle reflex and the cortisol stress response – were employed. Both show considerable interindividual variation which has been found in quantitative genetic studies to be at least partly based on genetic factors. In addition, the neural …
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ASSESSMENT OF NEUROTENSIN RECEPTOR AGONIST EFFECTS ON FEAR-POTENTIATED STARTLE
… female C57BL/J6 mice using the fear-potentiated startle (FPS) paradigm. Startle chambers were equipped with a shock-grid floor, fluorescent light, and an acoustic startle speaker. Conditioning took place between the light and floor shock, and test sessions measured startle to a 90 dB noise burst …
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Noise-induced cochlear neuronal degeneration and its role in hyperacusis -- and tinnitus-like behavior
… hyperacusis and tinnitus often occur following acoustic overexposure. Although such exposure can also result in permanent threshold elevation, some individuals with noise-induced hyperacusis or tinnitus show clinically normal thresholds. Recent work in animals has shown that noise exposure can …
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Der Einfluss von S-Ketamin und N,N-dimethyltrytamine (DMT) auf die Präpulsinhibition und die attentive Modulation des Startlereflexes : eine humanexperimentelle Untersuchung zum Modellpsychoseparadigma
Prepulse inhibition (PPI) of the acoustic startle reflex is a well established model for sensorimotor gating. Sensorimotor gating and also habituation are considered to serve as mechanisms that protect early stimulus processing and prevent the organism from experiencing sensory overload. …
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Studies of generalized worry in college students
… motivational system was probed using the acoustic startle response, and startle modification by visually presented words was used to quantify threat perception across various stages of information processing. Chronic high worriers exhibited word-induced startle facilitation at all stages …
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Effects of perinatal phencyclidine treatment on neuronal viability, N-methyl-D-aspartate receptor regulation and schizophrenic-like behaviors
… and deficits in sensorimotor gating (PPI of acoustic startle). Work within this dissertation discovered that PCP induces neurotoxicity in developing pups in a manner that is highly regulated affecting the distribution, composition, number, and function of NMDAR and that this loss of cortical …
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Eyelid conditioning in mice reveals an interaction between stress and familial Alzheimer's disease
… tested. Additionally, 3xTg mice produced greater acoustic startle. Both behavioral phenotypes are consistent with heightened stress response. On the other hand, mice harboring a single knock-in PS1 mutation aged ~16 months learned the task poorly compared to littermate controls. Enhanced …
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Blast-Induced Tinnitus: A Combined Behavioral, Memri, And Electrophysiology Study
… gap detection and pre-pulse inhibition (PPI) acoustic startle reflex paradigms; the changes of thresholds of the hearing was evaluated with auditory brainstem response (ABRs), the change in the level of anxiety was evaluated with elevated plus maze; and the change in the status of memory was …
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Characterization of a novel recombinant inbred mouse model of high fear
… of trauma cues, hyperarousal (exaggerated startle) and negative alterations in cognition and mood (anhedonia). Not all individuals exposed to trauma develop PTSD, while some individuals are susceptible, some are remarkably resilient. Genetic risk factors account for up to ~30-40% of …
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mGluR5 Involvement in Methamphetamine Reward and the Co-Morbidity of Schizophrenia and Stimulant Use Disorders
… the use of pre-pulse inhibition (PPI) of the acoustic startle response. PPI is defined as a normal suppression of the startle response when a weaker acoustic stimulus is presented before a louder startling acoustic stimulus. The current dissertation project utilized Meth-induced CPP, motor …
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