Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 2 of 2 for “"abnormal nuclear shape"”.
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HeLa에서 K-ras 과발현시 활성산소 발생에 의한 핵모양의 이상의 발생과 이중핵/다핵 세포 증가 현상 연구
Polyploidy and abnormal nuclear shapes are well known characteristics of cancer cells. K-Ras is frequently mutated in many cancers. One of the oncogene mutants, K-RasV12 has been reported to generate reactive oxygen species (ROS). We recently observed that increased ROS generates polyploidy and …
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The Application of a Statistical Model Investigating Reactive Oxygen Species in Premature Ageing Syndromes
… the accumulation of immature prelamin A at the nuclear membrane. As a result of increased understanding of the defects in HGPS arising from LMNA mutations a number of therapeutic routes are currently being trialled, but with little success. Work in my supervisor’s laboratory has suggested that …