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Showing 1 to 2 of 2 for “"aGalCer"”.

  1. Uncovering Novel Mechanism of Immune Modulation of Invariant Natural Killer T Cells By Liposomal Α-Galactosylceramide

    … α-GalCer. Our findings suggest that Liposomal aGalCer requires early endosomal recycling for association with CD1d. In the future, we plan to investigate the visual and kinetic sites of α-GalCer:CD1d loading using confocal microscopy, and impact on immunologic synapse formation.</p>

    uthsc Repository record for Uncovering Novel Mechanism of Immune Modulation of Invariant Natural Killer T Cells By Liposomal Α-Galactosylceramide (opens in a new tab)

  2. Structure-Activity Studies of Glycosphingolipids as Antigens of Natural Killer T Cells

    … of antigens, analogs of the model compound alphaGalCer (KRN-7000) have been synthesized. These include fluorophore-appended 6”-amino-α-galactosylceramides and N-alkenoyl GSLs, such as PBS-57, a potent alphaGalCer surrogate useful in NKT cell stimulation studies. A nonantigenic …

    byu Repository record for Structure-Activity Studies of Glycosphingolipids as Antigens of Natural Killer T Cells (opens in a new tab)