Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 47 for “"Zygote"”.
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Short-term recovery from a volume increase in the mouse zygote: Characteristics of regulatory volume decrease in vitro.
Mouse zygotes have been shown to recover from an imposed increase in volume, a process known as a regulatory volume decrease or RVD, via separate but functionally coupled Cl- and K+ channels. The objectives of this thesis were to further determine some of the characteristics of these Cl- and K+ …
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The Response of a protandrous species to exploitation, and the implications for management: a case study with patellid limpets
A zygote production model for the patellid limpet Patella vulgata has been developed to examine the effect of exploitation on the reproductive output of a protandrous (male to female sequential) hermaphrodite. Patellid limpets are broadcast spawners which can have specific implications for the …
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OVERT AND LATENT PATHWAYS OF POLARITY SPECIFICATION IN ZYGOTES: THE HAPLOID-TO-DIPLOID TRANSITION
… fusion and nuclear fusion, culminating in zygote formation. Following substantial remodeling of the cell wall, plasma membrane, and redistribution of cytoplasmic constituents, the newly-minted zygote enters the mitotic cell cycle and must establish a polarization axis for initial bud …
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The biology and ecology of Bifurcaria brassiceaformis (Kütz) Barton (Phaeophyta, Fucales)
… in the low-shore. Observations on the method of zygote attachment revealed that attachment of the species resembles that of the European Bifurcaria and Halidrys siliguosa which both also display delayed rhizoidal development and initially attach by means of a mucilage secretion of the zygote …
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Alternative rownstream roles for Ste2p and an α-arrestin in sacccharomyces cerevisiae mating
… on downstream mating projection formation and zygote formation events. Our findings indicate that Ste2p possess as specific residues that govern its relative bias for mediating MAPK signaling or mating events. Relative dose response experiments accounting for systemic and observation bias for …
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Learning a long healthy aging
… is formed from the DNA code within a person's zygote. As the body is programmatically built from the zygote, the swarms of RNA/DNA greatly increase, eventually forming the neurological system and kick-starting it to become intelligent. The human body is gradually but continuously changing; we …
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Exploring functional significance of asymmetric DNA methylation in early mammalian development
… mouse are present in the mature oocyte and the zygote. The enzymes responsible for establishing and maintaining its levels are the de novo Dnmts (3a and 3b), among which the activity of Dnmt3a2 towards CH seems regulated, suggesting a specific rather than an unspecific role. In ES cells, CH …
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An Analysis of Morphogenetic Movements on the Marginal Indentations of the Chick Embryo Yolk Sac
… of a multicellular organism from a single-celled zygote depends upon the processes of growth, differentiation, and morphogenesis. The classification of an organism as multicellular necessitates the involvement of the growth process, since multicellularity implies the production of additional …
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Lineage tracing of normal human development and childhood cancers
… phylogenetic tree of human development with the zygote at the root. Reconstructing phylogenies of human development requires readouts of somatic mutations present in single cells. Recently, low-input whole-genome sequencing following laser-capture microdissection has allowed us to reliably call …
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Trophoblast specification and differentiation potential in early human and non-human primate embryogenesis
… RNA sequencing dataset was generated from zygote to postimplantation embryos at Carnegie stage (CS) 7. Postimplantation samples were isolated from in utero embryos using laser capture dissection, enabling spatial reconstruction of trophoblast expression patterns and virtual reconstruction …
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A novel compound heterozygous NEB mutationin Korean patients with intellectual disability, epilepsy,and acongenital myopathy
… I concluded that this novel compound hetero zygote NEB mutation might be the disease-causing mutation underlying the patients’ clinical phenotypes.
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Transdifferentiation of fibroblasts to neural stem cells
… and epigenetic changes that occur as a zygote transforms into an adult organism. This process can be reversed by the overexpression of transcription factors Oct4, Sox2, Klf4, and c-Myc, which reprogram a differentiated cell!s nucleus to one that is transcriptionally and epigenetically …
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FLP-mediated conditional loss of an essential gene to facilitate complementation assays
… of the complementing cDNA in the egg cell and zygote following floral-dip transformation. The utility of this system is being tested using various experimental derivatives of the essential sucrose-proton symporter, AtSUC2, which is required for photoassimilate transport.
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Ein komplettes Embryo-Kultur-System zur Produktion transgener Hühner
… mit der Möglichkeit, eine Mikroinjektion in die Zygote durchzuführen. Anschließend erfolgt die Inkubation über ein Drei-Schritte-System in <br>verschiedenen Gastschalen bis zum Schlüpfen. <br>Die erste Phase dient dazu, die Bedingungen, wie sie im Eileiter herrschen, nachzu-ahmen. Auch in Phase …
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The role of inherited determinants and embryonic-extraembryonic cell interactions in models of mammalian embryogenesis
… cell of the newly developing embryo called the zygote. The mechanisms by which this single cell generates a fully formed organism have long been the subject of study of experimental biologists. Initially, embryonic development is reliant on maternally inherited determinants (e.g., RNA, proteins) …
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The Effects of Low Temperature on Survival of Rabbit Ova
… the problem of in situ placing the transferable zygote into the genital tract of the recipient so that nidation and embryonic growth can continue is far from being well perfected. In view of the problems that confront the workers in the field of ova transfer of rabbit ova. Because of the many …
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The physics of cell-fate choice
… All such cells arise from a single cell--- the zygote--- and acquire the various cell fates seen in adult organisms. The different cell types are characterized by distinct, cell-fate-specific gene expression patterns. Cells of different types can also exhibit varying metabolic states depending …
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Contribution of Lsh to DNA methylation reprogramming in embryonic stem cell, epiblast stem cell and embryoid body model systems
… erasure of the mark after fertilisation of the zygote. Genome-wide patterns of DNA methylation are subsequently re-established in the implanting blastocyst by de novo DNA methyltransferases Dnmt3a and Dnmt3b along with their catalytically inactive co-factor Dnmt3l, while these DNA methylation …
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ESTABLISHMENT IN CULTURE OF MOUSE AND HUMAN STEM CELLS WITH EXPANDED FATE POTENTIAL
The zygote and blastomeres of cleavage stage mouse embryos have the capacity to differentiate to the embryonic and both extra-embryonic lineages and are considered functionally totipotent. Until now, it has not been possible to establish stable cell lines that resemble these totipotent-like cells. …
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The Polycomb Complex 2 contributes to developmental delay when histone methylation is inappropriately inherited
… to reset the epigenetic landscape in the new zygote. During maternal reprogramming of histone methylation in <em>C. elegans</em>, H3K4me is removed by the H3K4 demethylase, SPR-5, and H3K9me is subsequently added by the histone methyltransferase, MET-2. Recently, it was demonstrated that SPR- …
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