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Showing 1 to 1 of 1 for “"Zuonin A"”.

  1. Elucidating binding modes of zuonin A enantiomers to JNK1 via in silico methods

    Dykstra, Daniel WilliamThe University of Texas at Austin2013

    … and cancer conditions. Enantiomers of the lignan zuonin A, (-)-zuonin A and (+)-zuonin A, have been shown to bind to JNK isoforms with similar affinity and disrupt protein-protein interactions at JNK's D-recruitment site, making them a good candidate for specific non-ATP competitive inhibitors. …

    texas Repository record