Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 9 of 9 for “"Zolpidem"”.
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Effect of Zolpidem, Zaleplon, and Ramelton on cognitive functioning after awakening from napping
… sedative hypnotic drugs zaleplon (Sonata) and zolpidem (Ambien) are not chemically like benzodiazepines, they induce sleep by binding to the same gamma-aminobutyric acid (GABA) receptors in the central nervous system. They may be less likely than benzodiazepine medications to disrupt natural …
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Repeated Zolpidem Treatment Effects on Sedative Tolerance, Withdrawal, mRNA Levels, and Protein Expression
<p> Zolpidem and benzodiazepines (BZs) potentiate the inhibitory action of gamma-Aminobutyric acid (GABA) by allosterically binding to GABAA receptors (GABAAR). Prolonged use of GABAAR positive allosteric modulators (PAM) can lead to behavioral tolerance, the diminished response to the same drug …
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Developing individualized ground testing protocols for use of sleep medications in spaceflight
… may be needed to prevent loss of life of crew. Zolpidem has been used on spaceflight after ground testing. The medication has been tested and studies have shown few side effects after a complete night of sleep. Few studies have been done on abrupt awakening after taking this medication. This …
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Insomnie in der Allgemeinarztpraxis. Eine epidemiologische Studie in Freiburg und Göttingen
… 23,6%, trizyklischen <br>Antidepressiva 19,2%, Zolpidem oder Zopiclon 15,7%), 120 erhielten nichtmedikamentöse <br>Empfehlungen. <br>Die Wirksamkeit der nichtmedikamentösen Behandlung wurde von den Hausärzten schlechter eingeschätzt als von den Patienten.
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Sublingual drug delivery: In vitro-in vivo correlation
… evaluated by predicting in vivo performance of Zolpidem and Propranolol following sublingual administration in human beings and comparing area under the plasma concentration-time curve. Percent prediction error was 12.02% and less than 10% (4.69, 6.69, 5.02 for 1, 1.75 and 3 mg dose, …
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A retrospective review of the utilization of Benzodiazepines and Z-drugs in selected private community pharmacies in Namibia: 2017-2022
… of benzodiazepines and Z-drugs was highest with Zolpidem (6.07 DDDs/1000 population) compared to other benzodiazepines and Z-drugs. Over 54% of the dispensing encounters of benzodiazepines and Z-drugs were repeat prescriptions of Z-drugs. From 2017 to 2022, the consumption of Z-drugs increased …
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Development of guidelines for high-risk medication dispensing
… (n=16), followed by warfarin (n=13) and zolpidem (n=11). Guidelines to improve the dispensing process were developed for the three most commonly dispensed high-risk medications namely the direct oral anticoagulants, warfarin and insulin. A focus group consisting of four general …
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Examining the Roles of GABAA Receptor Subtypes in Anxiety and Anxiolysis: Focusing on the Basolateral Amygdala
… of the<em> <em>α1</em>-<em>selective PAM zolpidem</em> </em>in WT mice produced slight anxiolytic-like effects with a narrow therapeutic window that overlapped with prominent motor-inhibiting effects. Systemic injection of the α3-selective PAM TP003 produced marked anxiolytic-like effects …
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Adecuación de la prescripción en pacientes crónicos y polimedicados en el área sanitaria II del Principado de Asturias
… y el uso de benzodiazepinas, antipsicóticos, zolpidem o antihistamínicos en pacientes con demencia o trastornos cognitivos, como criterios considerando el diagnóstico. 3) Al aplicar los criterios STOPP 2014: cualquier fármaco prescrito sin indicación basada en la evidencia y cualquier fármaco …