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Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 8 of 8 for “"Zinc Complex"”.
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Synthesis of Functionalized Sustainable Polyesters via Controlled Ring-opening Polymerization of O-carboxyanhydrides
… mediated by a highly redox reactive manganese complex and a zinc-alkoxide. Mechanistic studies indicated that the ring-opening process proceeded via the Mn-mediated decarboxylation with alkoxy radical formation (Chapter 2). In addition to the polymerization, a two-step facile chemical recycling …
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Synthesis and Reactivity of Low Valent Main Group Element Complexes
The β-diketiminate aluminum(I) complex NacNacAl (III-1) was shown to activate a range of substrates containing robust single and double bonds. Compound III-1 oxidatively adds a variety of H–X bonds (X = H, B, Al, C, Si, N, P, O) to give a series of four-coordinate aluminum hydride derivatives …
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Zink-Peptid-Komplexe als Modellsubstanzen natuerlicher Metalloproteine
Mit einem Teilgebiet der Chemie der Lebensprozesse beschäftigt sich der Zweig der Bioanorganischen Chemie. Ein spezielles Metallion, das Zink, wurde in der vorliegenden Arbeit näher betrachtet, Eine Ansatzmöglichkeit zur isolierten Betrachtung der Koordination des Metallions ist es, Modelle zu …
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Synthesis and Evaluation of New Antimicrobial Agents and Novel Organic Fluorophores
… a new family of pyrazole ligands, their zinc(II) complexes and to evaluate their antmicrobial activity. The overall goal was to improve the antimicrobial activity of both ligand and metal salt through the formation of the corresponding zinc complex. The first pyrazole ligands synthesized …
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Synthesis of Macrocyclic Polyamines and their Cu, Fe, Mn and Zn Complexes Targeting HIV (AIDS).
… HIV by different mechanisms. The manganese complex of pyridine-fused macrocyclic polyamine (M40401) has been found to reduce HIV-1 induced apoptosis of astroglial cells. Based on these findings, seventeen new compounds were designed and synthesized, including five macrocyclic polyamines …
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Bio-inspired iron and cobalt complexes featuring a secondary coordination sphere: ligand design, complexation, and modeling of enzymatic processes
… The isolation and characterization of synthetic complexes can help to identify analogous reactive intermediates in enzymatic systems, as well as model the reactivity observed in enzymes. This thesis reports on the synthesis and characterization of tetrapodal metal-ligand complexes containing …
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Mechanism of Action and Gold Nanoparticle Delivery of Pt(IV) Prodrugs of Cisplatin
<p>The antitumor effects of platinum(IV) complexes, considered prodrugs for cisplatin, are believed to be due to biological reduction of Pt(IV) to Pt(II), with the reduction products binding to DNA and other cellular targets. In this work we used pBR322 DNA to capture the products of reduction of …
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Biomimetic carboxylate-bridged diiron complexes : from solution behavior to modeling the secondary coordination sphere
… Secondary Coordination Sphere of Non-heme Metal Complexes Chapter 1 is a mini-review that covers systematic studies on the effect of hydrogen bonding donors on the properties of metal complexes. Generalizing across different metals studied in biomimetic chemistry, the review allows for the …